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HomeProduct name listAURAMINE O

AURAMINE O

Synonym(s):Basic Yellow 2;Solvent Yellow 34;Pyoctaninum aureum;Pyoktamin yellow, 4,4′-Bis-(dimethylamino)-benzophenonimide hydrochloride;4,4′-(Imidocarbonyl)bis(N,N-dimethylaniline) monohydrochloride

  • CAS NO.:2465-27-2
  • Empirical Formula: C17H22ClN3
  • Molecular Weight: 303.83
  • MDL number: MFCD00012484
  • EINECS: 219-567-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-23 13:36:13
AURAMINE O Structural

What is AURAMINE O?

Chemical properties

yellow powder

Chemical properties

Auramine is a yellow crystalline powder or flaky material.

The Uses of AURAMINE O

Certified for use by fluorescence microscopy in Churukian's modification of Truant's fluorescent method for acid fast bacilli on paraffin sections.

The Uses of AURAMINE O

Fluorescent stain for acid-resistant bacteria in sputum

What are the applications of Application

Auramine O is a stain used by fluorescence microscopy with a color index # of 41000

Definition

ChEBI: A hydrochloride obtained by combining 4,4'-carbonimidoylbis(N,N-dimethylaniline) with one molar equivalent of hydrogen chloride. A fluorescent stain for demonstrating acid fast organisms in a method similar to the Zieh Neelsen. It also can be used to make a fluorescent Schiff reagent.

General Description

Yellow flakes or powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

AURAMINE O is incompatible with strong oxidizing agents.

Hazard

Probable carcinogen.

Fire Hazard

Flash point data for AURAMINE O are not available. AURAMINE O is probably combustible.

Potential Exposure

Auramine is used industrially as a dye or dye intermediate for coloring textiles; paper, and leather. Also used as an antiseptic (a powerful antiseptic in ear and nose surgery, and treatment of gonorrhea) and fungicide. Human exposure to auramine occurs principally through skin absorption or inhalation of vapors. Low-level dermal exposure to the consumer may occur but would be limited to any migration of auramine from fabric, leather, or paper goods.

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Purification Methods

It crystallises from EtOH as the hydrochloride and is very slightly soluble in CHCl3, UV: 434nm ( 370). The free base (carbinolamine) has m 136o (from *C6H6). [Goldacre & Phillips J Chem Soc 1724 1949, Conrad et al. Biochemistry 9 1540 1970, Beilstein 14 IV 256.]

Properties and Applications

TEST ITEMS

SPECIFICATION

APPEARANCE

DARK YELLOWPOWDER

SHADE

BRIGHT YELLOWISH

HEAT RESISTANCE

280 °C min

DENSITY

1.07 g/cm 3

WATER FASTNESS

4-5

LIGHT FASTNESS

1-2

BLEACHABILITY (OXIDATIVE)

4

BLEACHABILITY (REDUCTIVE)

3

WATER SOLUBILITY AT 20 °C

10 g/L min

WATER INSOLUBLE

1.0% max

MOISTURE

3.0% max

TINTING STRENGTH

100-105 %

WEIGHT METAL TOTAL

50ppm max

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Incinerate in furnace with afterburner and scrubber.

Properties of AURAMINE O

Melting point: >250 °C (dec.)(lit.)
storage temp.  Inert atmosphere,Room Temperature
solubility  10g/l
form  Powder/Solid
Colour Index  41000
pka 9.8, 10.7(at 25℃)
color  Yellow to ochre-yellow
PH 6-7 (10g/l, H2O, 20℃)
PH Range 6.5
Water Solubility  Soluble in water or ethanol
λmax 370 nm, 432 nm
BRN  4030061
Stability: Stable. Incompatible with strong oxidizing agents.
Biological Applications Detecting bacteria; treatment of cancers,cardiovascular disease,diabetesassociated pain,mechanical allodynia,metabolic syndrome,protozoan infections in fish; targeted drug delivery; as fungal inhibitors
CAS DataBase Reference 2465-27-2(CAS DataBase Reference)
NIST Chemistry Reference Aniline, 4,4'-(imidocarbonyl)bis-(n,n-dimethyl)-, hydrochloride(2465-27-2)
EPA Substance Registry System Auramine, monohydrochloride (2465-27-2)

Safety information for AURAMINE O

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
ghs
Environment
GHS09
GHS Hazard Statements H302:Acute toxicity,oral
H319:Serious eye damage/eye irritation
H351:Carcinogenicity
H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P201:Obtain special instructions before use.
P273:Avoid release to the environment.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for AURAMINE O

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