AURAMINE O
Synonym(s):Basic Yellow 2;Solvent Yellow 34;Pyoctaninum aureum;Pyoktamin yellow, 4,4′-Bis-(dimethylamino)-benzophenonimide hydrochloride;4,4′-(Imidocarbonyl)bis(N,N-dimethylaniline) monohydrochloride
- CAS NO.:2465-27-2
- Empirical Formula: C17H22ClN3
- Molecular Weight: 303.83
- MDL number: MFCD00012484
- EINECS: 219-567-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is AURAMINE O?
Chemical properties
yellow powder
Chemical properties
Auramine is a yellow crystalline powder or flaky material.
The Uses of AURAMINE O
Certified for use by fluorescence microscopy in Churukian's modification of Truant's fluorescent method for acid fast bacilli on paraffin sections.
The Uses of AURAMINE O
Fluorescent stain for acid-resistant bacteria in sputum
What are the applications of Application
Auramine O is a stain used by fluorescence microscopy with a color index # of 41000
Definition
ChEBI: A hydrochloride obtained by combining 4,4'-carbonimidoylbis(N,N-dimethylaniline) with one molar equivalent of hydrogen chloride. A fluorescent stain for demonstrating acid fast organisms in a method similar to the Zieh Neelsen. It also can be used to make a fluorescent Schiff reagent.
General Description
Yellow flakes or powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
AURAMINE O is incompatible with strong oxidizing agents.
Hazard
Probable carcinogen.
Fire Hazard
Flash point data for AURAMINE O are not available. AURAMINE O is probably combustible.
Potential Exposure
Auramine is used industrially as a dye or dye intermediate for coloring textiles; paper, and leather. Also used as an antiseptic (a powerful antiseptic in ear and nose surgery, and treatment of gonorrhea) and fungicide. Human exposure to auramine occurs principally through skin absorption or inhalation of vapors. Low-level dermal exposure to the consumer may occur but would be limited to any migration of auramine from fabric, leather, or paper goods.
Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Purification Methods
It crystallises from EtOH as the hydrochloride and is very slightly soluble in CHCl3, UV: 434nm ( 370). The free base (carbinolamine) has m 136o (from *C6H6). [Goldacre & Phillips J Chem Soc 1724 1949, Conrad et al. Biochemistry 9 1540 1970, Beilstein 14 IV 256.]
Properties and Applications
TEST ITEMS |
SPECIFICATION |
APPEARANCE |
DARK YELLOWPOWDER |
SHADE |
BRIGHT YELLOWISH |
HEAT RESISTANCE |
280 °C min |
DENSITY |
1.07 g/cm 3 |
WATER FASTNESS |
4-5 |
LIGHT FASTNESS |
1-2 |
BLEACHABILITY (OXIDATIVE) |
4 |
BLEACHABILITY (REDUCTIVE) |
3 |
WATER SOLUBILITY AT 20 °C |
10 g/L min |
WATER INSOLUBLE |
1.0% max |
MOISTURE |
3.0% max |
TINTING STRENGTH |
100-105 % |
WEIGHT METAL TOTAL |
50ppm max |
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
Waste Disposal
Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Incinerate in furnace with afterburner and scrubber.
Properties of AURAMINE O
Melting point: | >250 °C (dec.)(lit.) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | 10g/l |
form | Powder/Solid |
Colour Index | 41000 |
pka | 9.8, 10.7(at 25℃) |
color | Yellow to ochre-yellow |
PH | 6-7 (10g/l, H2O, 20℃) |
PH Range | 6.5 |
Water Solubility | Soluble in water or ethanol |
λmax | 370 nm, 432 nm |
BRN | 4030061 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
Biological Applications | Detecting bacteria; treatment of cancers,cardiovascular disease,diabetesassociated pain,mechanical allodynia,metabolic syndrome,protozoan infections in fish; targeted drug delivery; as fungal inhibitors |
CAS DataBase Reference | 2465-27-2(CAS DataBase Reference) |
NIST Chemistry Reference | Aniline, 4,4'-(imidocarbonyl)bis-(n,n-dimethyl)-, hydrochloride(2465-27-2) |
EPA Substance Registry System | Auramine, monohydrochloride (2465-27-2) |
Safety information for AURAMINE O
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09 |
GHS Hazard Statements |
H302:Acute toxicity,oral H319:Serious eye damage/eye irritation H351:Carcinogenicity H411:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P201:Obtain special instructions before use. P273:Avoid release to the environment. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for AURAMINE O
Abamectin manufacturer
Orjet Intermediates Pvt. Ltd.
Rikin Industries
Unilex Colours and Chemicals Ltd
Satyawati Chemicals
New Products
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