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HomeProduct name listAPOFERRITIN

APOFERRITIN

Synonym(s):Ferritin, Apo-, Equine Spleen

  • CAS NO.:9013-31-4
  • Empirical Formula: NULL
  • Molecular Weight: 0
  • MDL number: MFCD00081365
  • Update Date: 2024-10-29 18:21:28

What is APOFERRITIN?

The Uses of APOFERRITIN

Apoferritin is a gel filtration molecular weight marker that can be used in gel filtration chromatography and protein chromatography. Apoferritin has the ability to demetallate hemin and to metallate protoporphyrin. Apoferritin is used as a novel nanocarrier to load methylene blue (MB) and demonstrate its potential applications for photodynamic therapy of cancer.

The Uses of APOFERRITIN

Apoferritin from equine spleen has been used:

  • to determine its partition coefficients in phase systems
  • in NaCl for iron loading of cultured cells
  • in in situ liquid scanning transmission electron microscope for imaging the interface of biology and nanotechnology

The Uses of APOFERRITIN

Apoferritin is a gel filtration molecular weight marker that can be used in gel filtration chromatography and protein chromatography. Apoferritin has the ability to demetallate hemin and to metallate protoporphyrin IX.

Biochem/physiol Actions

This protein shell of ferritin lacking iron is widely used for the calibration of gel filtration columns and sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis. It is very abundant in beta-cells of the pancreas where it acts as an anti-oxidant. When added to cultured endothelial cells apoferritin is taken up in a dose-responsive manner and appears to protect the cells from oxidant-mediated cytolysis.

Properties of APOFERRITIN

storage temp.  -20°C
solubility  Reconstitute in 0.15M NaCl
form  White lyophilized solid
color  clear to slightly hazy, solution

Safety information for APOFERRITIN

Computed Descriptors for APOFERRITIN

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