ansamitocin P-3
- CAS NO.：66584-72-3
- Empirical Formula: C32H43ClN2O9
- Molecular Weight: 635.14
- MDL number: MFCD00274586
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-06 19:41:26
What is ansamitocin P-3?
Description
Ansamitocin P 3 is a macrocyclic antitumor antibiotic that works by depolymerizing microtubules in both interphase and mitosis, and perturbs chromosome segregation.
The Uses of ansamitocin P-3
Ansamitocin P-3 is an antitumor agent that binds to cell division protein FtsZ in Actinosynnema pretiosum.
Definition
ChEBI: A polyketide antibiotic that is isolated from Actinosynnema pretiosum and also exhibits antitumour activity.
Properties of ansamitocin P-3
| Melting point: | 190-192℃ |
| Boiling point: | 833.1±65.0 °C(Predicted) |
| Density | 1.29 |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO: 100 mg/mL (157.45 mM);Ethanol: 55 mg/mL (86.60 mM) |
| form | Solid |
| pka | 9.82±0.70(Predicted) |
| color | White to Off-White |
| Water Solubility | Water: Insoluble |
Safety information for ansamitocin P-3
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for ansamitocin P-3
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