ANB-NOS
Synonym(s):N-(5-Azido-2-nitrobenzoyloxy)succinimide;N-Succinimidyl 5-azido-2-nitrobenzoate
- CAS NO.：60117-35-3
- Empirical Formula: C11H7N5O6
- Molecular Weight: 305.21
- MDL number: MFCD00054962
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-22 14:56:24
What is ANB-NOS?
Description
ANB-NOS Crosslinker contains a nitrophenyl azide group and an amine reactive NHS ester group. It is also able to react with nucleophiles.
The Uses of ANB-NOS
Anb-Nos Crosslinker can be used for devices implanted in the eyes to treat glaucoma and/or dry eye.
The Uses of ANB-NOS
Photoactive, heterobifunctional cross-linking reagent. Typically, initial reaction couples via ester to primary amine by amide bond formation in the pH range 6.5-8.5. Second bonding occurs during UV irradiation (250-350 nm) via reactive nitrene. The latter bonding is rapid and non-specific.
What are the applications of Application
5-Azido-2-nitrobenzoic acid N-hydroxysuccinimide ester is a nitrate-containing, aryl azide-based, amine- and photoreactive crosslinker
Properties of ANB-NOS
| Melting point: | 131-133°C |
| storage temp. | 2-8°C |
| solubility | ethyl acetate: 25 mg/mL |
| form | powder |
| color | yellow |
| BRN | 1555224 |
Safety information for ANB-NOS
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for ANB-NOS
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