ANB-NOS

Synonym(s):N-(5-Azido-2-nitrobenzoyloxy)succinimide;N-Succinimidyl 5-azido-2-nitrobenzoate

CAS NO.：60117-35-3
Empirical Formula: C11H7N5O6
Molecular Weight: 305.21
MDL number: MFCD00054962
SAFETY DATA SHEET (SDS)
Update Date: 2024-03-22 14:56:24

What is ANB-NOS?

Description

ANB-NOS Crosslinker contains a nitrophenyl azide group and an amine reactive NHS ester group. It is also able to react with nucleophiles.

The Uses of ANB-NOS

Anb-Nos Crosslinker can be used for devices implanted in the eyes to treat glaucoma and/or dry eye.

The Uses of ANB-NOS

Photoactive, heterobifunctional cross-linking reagent. Typically, initial reaction couples via ester to primary amine by amide bond formation in the pH range 6.5-8.5. Second bonding occurs during UV irradiation (250-350 nm) via reactive nitrene. The latter bonding is rapid and non-specific.

What are the applications of Application

5-Azido-2-nitrobenzoic acid N-hydroxysuccinimide ester is a nitrate-containing, aryl azide-based, amine- and photoreactive crosslinker

Properties of ANB-NOS

Melting point:	131-133°C
storage temp.	2-8°C
solubility	ethyl acetate: 25 mg/mL
form	powder
color	yellow
BRN	1555224

Safety information for ANB-NOS

Precautionary Statement Codes

P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.