amphotalide
- CAS NO.:1673-06-9
- Empirical Formula: C19H20N2O3
- Molecular Weight: 324.378
- MDL number: MFCD00866729
- EINECS: 2168099
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is amphotalide?
Originator
Amphotalide,ZYF Pharm Chemical
Definition
ChEBI: Amphotalide is a member of phthalimides.
Manufacturing Process
A mixture of 5-phthalimidopentyl bromide (Drake and Garman, J.Amer. Chem.
Sec, 1949, 71, 2426) (296.0 g) and potassium p-nitrophenoxide (177.0 g) in
ethanol (1.5 L) was stirred mechanically, boiled under reflux for 20 h,
concentrated to half its volume, cooled and filtered. The product was washed
with water, dried and crystallised from acetone, giving 1-p-nitrophenoxy-5-
phthalimidopentane, melting point 123°-124°C.
The foregoing 1-p-nitrophenoxy-5-phthalimidopentane (100.0 g) in ethanol (1
L) was reduced by hydrogen over 2% of platinum oxide at 74°C/73 lb. per sq.
in. The filtered solution on cooling gave L-p-aminophenoxy-5-phthalimidopentane, melting point 111°-112° C (recrystallisation from
ethanol).
Therapeutic Function
Antischistosomal
Properties of amphotalide
Melting point: | 113-114° |
Safety information for amphotalide
Computed Descriptors for amphotalide
New Products
(R)-3-Aminobutanenitrile Hydrochloride 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION SODIUM VALPROATE Diclofenac Sodium Methylcobalamin (vitamin B12) VILDAGLIPTIN ACICLOVIR AMOXICILLIN (AMOXYCILLIN) TRIHYDRATE Desloratidine Related compound B Folic Acid Impurity G Glycopyrronium Bromide EP Impurity I Eltrombopag N-Oxide Impurity Di-Nitroso Acyclovir Impurity K DLRD N-OxideRelated products of tetrahydrofuran
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