Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listPhthalide

Phthalide

Synonym(s):1-Isobenzofuranone

  • CAS NO.:87-41-2
  • Empirical Formula: C8H6O2
  • Molecular Weight: 134.13
  • MDL number: MFCD00005906
  • EINECS: 417-930-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:52
Phthalide Structural

What is Phthalide?

Description

White powder; sweet tonka, coumarin, powdery, coconut, phenolic, lactonic aroma.
Phthalide powder

The Uses of Phthalide

Phthalide may be used in scaffolds for the design of high potency monoamine oxidase (MAO) inhibitors.

Definition

ChEBI: A gamma-lactone that is 1,3-dihydro-2-benzofuran in which the hydrogens at position 1 are replaced by an oxo group.

Aroma threshold values

Low strength odor, Tonka type.

Taste threshold values

Sweet coumarin, coconut, creamy, anisic, green vegetable, floral taste at 100 ppm in water.

Synthesis Reference(s)

Chemistry Letters, 23, p. 1149, 1994
The Journal of Organic Chemistry, 68, p. 9423, 2003 DOI: 10.1021/jo0350763
Tetrahedron Letters, 7, p. 6097, 1966

Flammability and Explosibility

Not classified

Pharmacology

Systemic fungicide giving effective preventive control of the rice blast fungus in rice as foliar spray.

Purification Methods

Crystallise phthalide from water (75mL/g) and dry it in air on filter paper. [Beilstein 17/10 V 7.]

Toxicity evaluation

Mammalian toxicology. Oral: Acute oral LD50 for rats and mice >10000 mg/kg. Skin and eye: Acute percutaneous LD50 for rats and mice >10000 mg/kg. Not a shaved skin irritant, eye irritant (rabbits). Inhalation LC50 (4 h) for rats >4.1 mg/L air. NOEL: (2 yr) for rats 2000, mice 100 mg/kg diet.

Properties of Phthalide

Melting point: 71-74 °C (lit.)
Boiling point: 290 °C (lit.)
Density  1.1
refractive index  1.5360 (estimate)
FEMA  4195 | PHTHALIDE
Flash point: 152 °C
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Crystalline Powder
color  White to light beige
Odor at 100.00 %. sweet tonka coumarin powdery coconut phenolic lactonic
Water Solubility  sparingly soluble
BRN  114632
Dielectric constant 36.0(23℃)
CAS DataBase Reference 87-41-2(CAS DataBase Reference)
NIST Chemistry Reference 1(3H)-Isobenzofuranone(87-41-2)
EPA Substance Registry System Phthalide (87-41-2)

Safety information for Phthalide

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H319:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for Phthalide

InChIKey WNZQDUSMALZDQF-UHFFFAOYSA-N

Phthalide manufacturer

Dodhia Group

1Y
Phone:+919619867345
Whatsapp: +91 9619867345
product: Phthalide 99%
Inquiry

Neugen Labs

1Y
Phone:+918133254502
Whatsapp: +91-8133254502
product: 87-41-2 Phthalide 98%
Inquiry

DL INTRACHEM

1Y
Phone:+91-9099014678
Whatsapp: +91-9099014678
product: 87-41-2 98%
Inquiry

DeFINE CHEMICALS

1Y
Phone:+91-9320057099
Whatsapp: +91-9320057099
product: Phthalide 98%
Inquiry

Asmee Chemicals

1Y
Phone:+91-9920257026
Whatsapp: +91-9920257026
product: Phthalide 87-41-2 98%
Inquiry

Anand Agencies

Maharashtra
Phone:91-9075014125
Whatsapp: 91-9075014125
product: Phthalide
Inquiry

Neugen Labs

Karnataka
Phone:91-8133254502
Whatsapp: 91-8133254502
product: Phthalide
Inquiry

ASM Organics

Andhra Pradesh
Phone:91-9866122393
Whatsapp: 91-9866122393
product: Phthalide
Inquiry

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.