AMINOMALONONITRILE P-TOLUENESULFONATE

CAS NO.：5098-14-6
Empirical Formula: C10H11N3O3S
Molecular Weight: 253.28
MDL number: MFCD00012848
EINECS: 225-817-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is AMINOMALONONITRILE P-TOLUENESULFONATE?

The Uses of AMINOMALONONITRILE P-TOLUENESULFONATE

Aminomalononitrile p-toluenesulfonate is a reagent for diazonamide synthesis via heck endocyclization. It may also have implications for developing IκB Kinase-β inhibitors.

The Uses of AMINOMALONONITRILE P-TOLUENESULFONATE

Aminomalononitrile p-toluenesulfonate was used in the syntheiss of 1-substituted 5-amino-4-cyano-2-hydroxyimidazoles.

Purification Methods

It forms colourless crystals on recrystallisation from MeCN (1.8g in 100mL) using activated charcoal. Wash the crystals with dry Et2O and dry them at 25o/1mm. Recovery is ~80%. [Ferris et al. Org Synth Coll Vol V 32 1973.]

Properties of AMINOMALONONITRILE P-TOLUENESULFONATE

Melting point:	174 °C (dec.) (lit.)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
form	Solid
color	Beige Powder,
Water Solubility	almost transparency
BRN	4050747
Stability:	Hygroscopic
CAS DataBase Reference	5098-14-6(CAS DataBase Reference)

Safety information for AMINOMALONONITRILE P-TOLUENESULFONATE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.