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HomeProduct name listAmifostine Thiol Dihydrochloride

Amifostine Thiol Dihydrochloride

Synonym(s):2-[(3-Aminopropyl)amino]ethanethiol dihydrochloride;WR-1065;WR-1065 dihydrochloride

Amifostine Thiol Dihydrochloride Structural

What is Amifostine Thiol Dihydrochloride?

Chemical properties

White Solid

The Uses of Amifostine Thiol Dihydrochloride

A metabolite of Amifostine.

What are the applications of Application

Amifostine Thiol Dihydrochloride is a metabolite of Amifostine

Biochem/physiol Actions

WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.

storage

Desiccate at -20°C

Properties of Amifostine Thiol Dihydrochloride

Melting point: 184-186°C
storage temp.  -20°C
solubility  H2O: ≥20mg/mL
form  powder
color  white to off-white
Stability: Hygroscopic

Safety information for Amifostine Thiol Dihydrochloride

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H318:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Amifostine Thiol Dihydrochloride

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