alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol)
Synonym(s):25-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-4,7,10,13,16,19-hexaoxa-22-azapentacosanoic acid 2,5-dioxo-1-pyrrolidinyl ester;Maleimide-PEG6-NHS ester
- CAS NO.：1137109-21-7
- Empirical Formula: C26H39N3O13
- Molecular Weight: 601.6
- MDL number: MFCD11041093
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol)?
Description
Mal-amido-PEG6-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
The Uses of alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol)
Heterobifunctional crosslinker with an ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 31.7 angstroms.
Properties of alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol)
| Melting point: | 54 - 57°C |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Acetonitrile (Slightly), Water (Slightly) |
| form | Solid |
| pka | 15.01±0.46(Predicted) |
| color | White to Off-White |
Safety information for alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol)
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol)
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