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HomeProduct name listFMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID

FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID

FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID Structural

What is FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID?

Description

Fmoc-N-amido-PEG3-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical properties

White powder

The Uses of FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID

1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic Acid has been used as a reactant for the preparation of vaccines.

Properties of FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID

Melting point: 43-46°C
Boiling point: 651.9±55.0 °C(Predicted)
Density  1.230
storage temp.  2-8°C
solubility  DMSO (Sparingly), Methanol (Slightly)
form  Solid
pka 4.28±0.10(Predicted)
color  White

Safety information for FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID

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