FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID

CAS NO.：867062-95-1
Empirical Formula: C24H29NO7
Molecular Weight: 443.49
MDL number: MFCD06656471
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-28 23:16:16

What is FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID?

Description

Fmoc-N-amido-PEG3-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical properties

White powder

The Uses of FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID

1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic Acid has been used as a reactant for the preparation of vaccines.

Properties of FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID

Melting point:	43-46°C
Boiling point:	651.9±55.0 °C(Predicted)
Density	1.230
storage temp.	2-8°C
solubility	DMSO (Sparingly), Methanol (Slightly)
form	Solid
pka	4.28±0.10(Predicted)
color	White

Safety information for FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.