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HomeProduct name listALPHA-HYDROXYFARNESYLPHOSPHONIC ACID

ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID

  • CAS NO.:148796-53-6
  • Empirical Formula: C15H27O4P
  • Molecular Weight: 302.35
  • MDL number: MFCD00216148
  • EINECS: 200-578-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-28 23:16:16
ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID Structural

What is ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID?

Description

α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations greater than 1 μM, α-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells.

What are the applications of Application

α-hydroxy Farnesyl Phosphonic Acid is an inhibitor of Ras and Farnesyl Transferase activity

Properties of ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID

storage temp.  −20°C
solubility  10 mM Na2CO3: freely soluble; ETOH: >25 mg/ml; PBS pH 7.2: <25 μg/ml
form  A crystalline solid

Safety information for ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID

Computed Descriptors for ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID

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