Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listAdrenosterone

Adrenosterone

Synonym(s):11-Ketoandrostenedione;4-Androstene-3,11,17-trione;Androst-4-ene-3,11,17-trione;Reichstein’s substance G

  • CAS NO.:382-45-6
  • Empirical Formula: C19H24O3
  • Molecular Weight: 300.39
  • MDL number: MFCD00003606
  • EINECS: 206-843-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-07-02 14:09:54
Adrenosterone Structural

What is Adrenosterone?

Chemical properties

Off-White to Pale Yellow Solid

The Uses of Adrenosterone

Androgenic activity;Androgenic steroid

Definition

ChEBI: Adrenosterone is a 3-oxo Delta(4)-steroid that is androst-4-ene carrying three oxo-substituents at positions 3, 11 and 17. It has a role as an androgen, a human urinary metabolite, a marine metabolite and an EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor. It is a 3-oxo-Delta(4) steroid, a 17-oxo steroid, an androstanoid and an 11-oxo steroid. It derives from a hydride of an androstane.

Benefits

Adrenosterone is sold as a dietary supplement since 2007 as a fat loss and muscle gaining supplement. It is thought to be a competitive selective 11βHSD1 inhibitor, which is responsible for activation of cortisol from cortisone. Thus preventing muscle breakdown, and contributing to a majority of its effects.

Purification Methods

Dissolve adrenosterone i n Me2CO, decolorise it with charcoal, filter, add H2O, Me2CO evaporate and the solid is recrystallised from aqueous EtOH. Also recrystallise it from Et2O or Et2O/pentane and dry it at 110o/0.1mm for 2hours. It can be sublimed under high vacuum. [Reichstein Helv Chim Acta 20 953, 979 1937, Mason et al. J Biol Chem 116 267 1936, Beilstein 7 III 4601.]

Properties of Adrenosterone

Melting point: 219-222 °C(lit.)
Boiling point: 381.62°C (rough estimate)
alpha  300 º (c=1 in chloroform)
Density  1.1381 (rough estimate)
refractive index  290 ° (C=0.2, EtOH)
storage temp.  Sealed in dry,Room Temperature
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly)
form  Solid
color  White to Off-White
optical activity [α]20/D +300°, c = 1 in chloroform
Water Solubility  98.49mg/L(23.5 ºC)
Merck  14,176
CAS DataBase Reference 382-45-6(CAS DataBase Reference)
NIST Chemistry Reference Androst-4-ene-3,11,17-trione(382-45-6)

Safety information for Adrenosterone

Computed Descriptors for Adrenosterone

InChIKey RZRPTBIGEANTGU-IRIMSJTPSA-N

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.