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148498-78-6

148498-78-6 structural image
Product Name: ADRENOMEDULLIN (HUMAN)
Formula: C264H406N80O77S3
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COMPUTED DESCRIPTORS

Molecular Weight 6029 g/mol
XLogP3 -28.6
Hydrogen Bond Donor Count 90
Hydrogen Bond Acceptor Count 90
Rotatable Bond Count 193
Exact Mass 6026.9542322 g/mol
Monoisotopic Mass 6024.9475225 g/mol
Topological Polar Surface Area 2690 Ų
Heavy Atom Count 424
Formal Charge 0
Complexity 15400
Isotope Atom Count 0
Defined Atom Stereocenter Count 54
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

A 52-amino acid peptide with multi-functions. It was originally isolated from PHEOCHROMOCYTOMA and ADRENAL MEDULLA but is widely distributed throughout the body including lung and kidney tissues. Besides controlling fluid-electrolyte homeostasis, adrenomedullin is a potent vasodilator and can inhibit pituitary ACTH secretion.