Ademethionine 1,4-Butanedisulfonate

CAS NO.：101020-79-5
Empirical Formula: C42H74N12O28S8
Molecular Weight: 1451.59
MDL number: MFCD11111819
EINECS: 600-154-4
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-17 17:32:32

What is Ademethionine 1,4-Butanedisulfonate?

The Uses of Ademethionine 1,4-Butanedisulfonate

Ademethionine 1,4-Butanedisulfonate is used in the synthesis of sulfonio-adenosyl-L-methionine (SAMe) salts.

The Uses of Ademethionine 1,4-Butanedisulfonate

Adenosine 1,4-butanedisulfonate sodium (SAMe) enteric-coated tablets are widely used to treat preciosis and intrahepatic cholestasis in cirrhosis, and can be used to treat intrahepatic cholestasis (ICP) during pregnancy.

Properties of Ademethionine 1,4-Butanedisulfonate

Melting point:	>48oC (dec.)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)
form	Solid
color	Off-White
Stability:	Hygroscopic
CAS DataBase Reference	101020-79-5(CAS DataBase Reference)

Safety information for Ademethionine 1,4-Butanedisulfonate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H227:Flammable liquids H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Ademethionine 1,4-Butanedisulfonate

InChIKey	PVCDYZJGZPCASW-FGEWMKOMNA-M
SMILES	C(CCCS(O)(=O)=O)S(O)(=O)=O.O[C@@H]1[C@@H]([C@@H](C[S+](C)CC[C@H](N)C(=O)O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O.C(CCCS([O-])(=O)=O)S([O-])(=O)=O \|&1:13,14,15,21,27,r\|