Acetylferrocene
Synonym(s):(Acetylcyclopentadienyl)cyclopentadienyliron;1-Ferrocenylethanone;Acetoferrocene
- CAS NO.:1271-55-2
- Empirical Formula: C12H12FeO10*
- Molecular Weight: 228.07
- MDL number: MFCD00001432
- EINECS: 215-043-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:52
What is Acetylferrocene?
Chemical properties
orange crystalline powder
The Uses of Acetylferrocene
1-Acetylferrocene was originally used in military or space field as an additive in rocket propellant, to promote the burning rate. Its ferrocenyl derivative has wide applications to biological and medical fields such as ferrocene-modified beta-lactam because of its physiological activity of anti-malarial, anti-tumor, bactericidal, anti-inflammatory, treatment of anemia, inhibition of enzymatic activity and so on by virtue of its unique structure and diverse properties.
What are the applications of Application
Acetylferrocene is an organoiron compound
Safety Profile
Poison by ocular and intravenous routes. A flammable liquid. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods
Orange-red crystals are obtained when it is recrystallised from isooctane or *C6H6, and then sublimed at 100o/1mm. The oxime has m 167-170o (from Et2O or aqueous EtOH). The semicarbazone has m 198-201o (from EtOH). [Richmond & Freiser J Am Chem Soc 77 2022 1955, Weinmayer J Am Chem Soc 77 3009 1955, Broadhead et al. J Chem Soc 650 1958, Beilstein 16 IV 1798.]
Properties of Acetylferrocene
Melting point: | 81-83 °C (lit.) |
Boiling point: | 160-163 °C (3.0004 mmHg) |
Density | >1 g/cm3 (20℃) |
Flash point: | 160-163°C/4mm |
storage temp. | Sealed in dry,Room Temperature |
form | Needle-Like Crystalline Powder |
color | Orange |
Water Solubility | insoluble |
Exposure limits | ACGIH: TWA 1 mg/m3 NIOSH: TWA 1 mg/m3 |
Stability: | Stable. Incompatible with strong oxidizing agents, reducing agents, strong acids, strong bases. |
CAS DataBase Reference | 1271-55-2(CAS DataBase Reference) |
NIST Chemistry Reference | Acetylferrocene(1271-55-2) |
EPA Substance Registry System | Ferrocene, acetyl- (1271-55-2) |
Safety information for Acetylferrocene
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
Precautionary Statement Codes |
P262:Do not get in eyes, on skin, or on clothing. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for Acetylferrocene
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