ACETOXYACETONE

Synonym(s):Acetonyl acetate

CAS NO.：592-20-1
Empirical Formula: C5H8O3
Molecular Weight: 116.12
MDL number: MFCD00042848
EINECS: 209-746-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-25 18:01:09

What is ACETOXYACETONE?

Chemical properties

Clear pale yellow to amber liquid

The Uses of ACETOXYACETONE

Acetoxyacetone is an building block in the synthesis of various pharmaceutical and organic compounds.

Definition

ChEBI: Acetoxyacetone is a carboxylic ester and a ketone.

Synthesis Reference(s)

The Journal of Organic Chemistry, 57, p. 4263, 1992 DOI: 10.1021/jo00041a036

Purification Methods

Distil it in a vacuum, then redistil it at atmospheric pressure. It is miscible with H2O, but is slowly decomposed by it. Store it in a dry atmosphere. The 2,4-dinitrophenylhydrazone has m 115-115.5o (from CHCl3/hexane). [Perkin Jr J Chem Soc 59 789 1891, Reich & Samuels J Org Chem 21 68 1956, Nef Justus Liebigs Ann Chem 335 260 1904, Beilstein 2 IV 297.]

Properties of ACETOXYACETONE

Melting point:	74.0-75.5 °C
Boiling point:	174-176 °C(lit.)
Density	1.075 g/mL at 20 °C(lit.)
refractive index	n20/D 1.415
Flash point:	71 °C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Soluble in diethyl ether, ethyl acetate and dichloromethane.
form	Liquid
color	Clear pale yellow to amber
Odor	fruity buttery dairy nutty
BRN	1749857
CAS DataBase Reference	592-20-1(CAS DataBase Reference)
EPA Substance Registry System	2-Propanone, 1-(acetyloxy)- (592-20-1)

Safety information for ACETOXYACETONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H227:Flammable liquids
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..…