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HomeProduct name list2-Naphthyl acetate

2-Naphthyl acetate

Synonym(s):β-Naphthyl acetate

  • CAS NO.:1523-11-1
  • Empirical Formula: C12H10O2
  • Molecular Weight: 186.21
  • MDL number: MFCD00004060
  • EINECS: 216-194-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:57
2-Naphthyl acetate Structural

What is 2-Naphthyl acetate?

Chemical properties

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The Uses of 2-Naphthyl acetate

2-Naphthyl Acetate is used in the staining of gels for esterase activity in the biological laboratories. An esterase substrate.

The Uses of 2-Naphthyl acetate

2-Naphthyl acetate has been used as a substrate:

  • in substrate sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) to examine the composition of lipases in larvae and adult specimens
  • in the preparation of zymograms to identify proteins with lipase activity
  • to measure non-specific esterase activity and β-esterase enzyme activity

Synthesis Reference(s)

Journal of the American Chemical Society, 91, p. 2162, 1969 DOI: 10.1021/ja01036a081

Purification Methods

Distil the acetate in a high vaccum and/or crystallise it from pet ether (b 60-80o) or dilute aqueous EtOH. The picrate has m 80o (from EtOH). [Beilstein 6 H 644, 6 I 313, 6 II 600, 5 III 2982, 6 IV 4267.]

Properties of 2-Naphthyl acetate

Melting point: 67-70 °C (lit.)
Boiling point: 132 °C / 2mmHg
Density  1.1032 (rough estimate)
refractive index  1.6010 (estimate)
storage temp.  -20°C
solubility  methanol: 0.1 g/mL, clear
form  powder to crystaline
color  White to Light yellow
Sensitive  Moisture Sensitive
BRN  1868291
CAS DataBase Reference 1523-11-1(CAS DataBase Reference)
NIST Chemistry Reference 2-Naphthyl acetate(1523-11-1)
EPA Substance Registry System 2-Naphthalenol, acetate (1523-11-1)

Safety information for 2-Naphthyl acetate

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H318:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Naphthyl acetate

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