2-Naphthyl acetate
Synonym(s):β-Naphthyl acetate
- CAS NO.：1523-11-1
- Empirical Formula: C12H10O2
- Molecular Weight: 186.21
- MDL number: MFCD00004060
- EINECS: 216-194-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-10-25 17:20:07
What is 2-Naphthyl acetate?
Chemical properties
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The Uses of 2-Naphthyl acetate
2-Naphthyl Acetate is used in the staining of gels for esterase activity in the biological laboratories. An esterase substrate.
The Uses of 2-Naphthyl acetate
2-Naphthyl acetate has been used as a substrate:
- in substrate sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) to examine the composition of lipases in larvae and adult specimens
- in the preparation of zymograms to identify proteins with lipase activity
- to measure non-specific esterase activity and β-esterase enzyme activity
Synthesis Reference(s)
Journal of the American Chemical Society, 91, p. 2162, 1969 DOI: 10.1021/ja01036a081
Purification Methods
Distil the acetate in a high vaccum and/or crystallise it from pet ether (b 60-80o) or dilute aqueous EtOH. The picrate has m 80o (from EtOH). [Beilstein 6 H 644, 6 I 313, 6 II 600, 5 III 2982, 6 IV 4267.]
Properties of 2-Naphthyl acetate
| Melting point: | 67-70 °C (lit.) |
| Boiling point: | 132 °C / 2mmHg |
| Density | 1.1032 (rough estimate) |
| refractive index | 1.6010 (estimate) |
| storage temp. | -20°C |
| solubility | methanol: 0.1 g/mL, clear |
| form | powder to crystaline |
| color | White to Light yellow |
| Sensitive | Moisture Sensitive |
| BRN | 1868291 |
| CAS DataBase Reference | 1523-11-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Naphthyl acetate(1523-11-1) |
| EPA Substance Registry System | 2-Naphthalenol, acetate (1523-11-1) |
Safety information for 2-Naphthyl acetate
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Naphthyl acetate
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