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HomeProduct name listAC-DEVD-AMC

AC-DEVD-AMC

Synonym(s):Ac-DEVD-AMC;Caspase-3 Substrate II, Fluorogenic - CAS 169332-61-0 - Calbiochem

AC-DEVD-AMC Structural

What is AC-DEVD-AMC?

The Uses of AC-DEVD-AMC

N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin has been used as a substrate for caspase-3 assay in human colon cancer cell line and in bone marrow mesenchymal stem cells.

Biochem/physiol Actions

Fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.

Properties of AC-DEVD-AMC

Boiling point: 1200.1±65.0 °C(Predicted)
Density  1.423±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  DMSO: 10 mM
form  powder
pka 4.09±0.10(Predicted)
color  white

Safety information for AC-DEVD-AMC

Computed Descriptors for AC-DEVD-AMC

InChIKey ALZSTTDFHZHSCA-RNVDEAKXSA-N

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