8-HYDROXYGUANOSINE
- CAS NO.：3868-31-3
- Empirical Formula: C10H13N5O6
- Molecular Weight: 299.24
- MDL number: MFCD00216136
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-04 20:04:50
What is 8-HYDROXYGUANOSINE?
Chemical properties
Crystalline Solid
The Uses of 8-HYDROXYGUANOSINE
A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro
The Uses of 8-HYDROXYGUANOSINE
It is a representative metabolite derived by the oxidation of Guanosine (G) and is regarded as a marker of oxidative stress in the cells.
What are the applications of Application
8-Hydroxyguanosine is a product of oxidative damage to RNA
Definition
ChEBI: 8-Hydroxyguanosine is a purine nucleoside.
Safety Profile
Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.
Properties of 8-HYDROXYGUANOSINE
| Melting point: | 232-235°C |
| Density | 2.43±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) Water (Slightly, Heated, |
| form | White to off-white powder. |
| pka | 7.75±0.20(Predicted) |
| color | White to Off-White |
| Stability: | Hygroscopic |
Safety information for 8-HYDROXYGUANOSINE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for 8-HYDROXYGUANOSINE
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