8-BR-CGMP
- CAS NO.：31356-94-2
- Empirical Formula: C10H11BrN5O7P
- Molecular Weight: 424.1
- MDL number: MFCD00038423
- SAFETY DATA SHEET (SDS)
What is 8-BR-CGMP?
The Uses of 8-BR-CGMP
8-Bromoguanosine 3'', 5'' -cyclic monophosphoric acid
Definition
ChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP bearing an additional bromo substituent at position 8 on the guanine ring. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activatin PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.
Properties of 8-BR-CGMP
| Density | 2.96±0.1 g/cm3(Predicted) |
| pka | 1.01±0.60(Predicted) |
Safety information for 8-BR-CGMP
Computed Descriptors for 8-BR-CGMP
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