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HomeProduct name list7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL

7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL

7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL Structural

What is 7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL?

Description

7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters, which are capable of forming covalent DNA adducts and inducing mutations.

Chemical properties

Yellow Solid

The Uses of 7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL

7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters, which are capable of forming covalent DNA adducts and inducing mutations.[Cayman Chemical]

The Uses of 7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL

7,8,9,10-Tetrahydro-benzo[a]pyren-7-ol is a Benzopyrene (B205800) derivative, activated by hepatic cytosol.

What are the applications of Application

7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is an oxygen compound used for research purposes

General Description

7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol (7-hydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene), a polycyclic aromatic hydrocarbon (PAH), is a substituted benzopyrene. Its bromination reaction with N-bromosaccharin (NBSac) has been investigated. The sulfotransferase-assisted activation of 7-hydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene to form electrophilic, mutagenic, or tumorigenic sulfuric acid ester metabolite, which binds covalently to DNA and leads to mutation, has been reported.

Properties of 7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL

Melting point: 142-144 °C(lit.)
Boiling point: 508.5±19.0 °C(Predicted)
Density  1.323±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.2 mg/ml
form  A crystalline solid
pka 14.36±0.20(Predicted)
color  Light brown to brown

Safety information for 7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H332:Acute toxicity,inhalation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL

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