7-Aminoindole
Synonym(s):(Indol-7-yl)amine;7-Indolylamine
- CAS NO.：5192-04-1
- Empirical Formula: C8H8N2
- Molecular Weight: 132.16
- MDL number: MFCD02093960
- EINECS: 623-757-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:39
What is 7-Aminoindole?
The Uses of 7-Aminoindole
Reactant for preparation of:• ;Fluorescent anion receptors and sensors1,2• ;Sulfate receptors3• ;Protein Kinase C θ (PKCθ) inhibitors4• ;Factor Xa Inhibitors5• ;Aurora kinase inhibitor• ;Antagonist of Mineralocorticoid Receptor6• ;Potent histone deacetylase (HDAC) inhibitors7• ;TRPV1 antagonists8• ;Derivatives of N-(7-indolyl)benzenesulfonamide as cell cycle inhibitors9
The Uses of 7-Aminoindole
Reactant for preparation of:
- Fluorescent anion receptors and sensors
- Sulfate receptors
- Protein Kinase C θ (PKCθ) inhibitors
- Factor Xa Inhibitors
- Aurora kinase inhibitor
- Antagonist of Mineralocorticoid Receptor
- Potent histone deacetylase (HDAC) inhibitors
- TRPV1 antagonists
- Derivatives of N-(7-indolyl)benzenesulfonamide as cell cycle inhibitors
What are the applications of Application
7-Aminoindole is a potent HDAC, PKC, and ARK inhibitor
Definition
ChEBI: 1H-indol-7-amine is an indolamine.
Properties of 7-Aminoindole
| Melting point: | 96-100 °C |
| Boiling point: | 354.0±15.0 °C(Predicted) |
| Density | 1.268±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 17.68±0.30(Predicted) |
| color | Black |
| Sensitive | Air Sensitive |
| BRN | 471787 |
| CAS DataBase Reference | 5192-04-1(CAS DataBase Reference) |
Safety information for 7-Aminoindole
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 7-Aminoindole
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