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HomeProduct name list(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride

Synonym(s):(−)-(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol hydrochloride;(−)-N 0437;N 0923;Neupro;SPM 962

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Structural

What is (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride?

Chemical properties

White to Off-White Solid

The Uses of (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride

It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.

What are the applications of Application

Rotigotine Hydrochloride is a D2DR and D3DR agonist

Biochem/physiol Actions

Rotigotine is a dopamine receptor agonist with preference for D3 receptors over D2 and D1. As such, it is an effective anti-Parkinsonian agent. Racemic rotigotine is about 50 times as potent as quinpirole, the gold standard D2 agonist.

storage

room temperature (desiccate)

Properties of (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride

Melting point: 114-117°C
Density  1.2g/cm3 at 20℃
vapor pressure  0-0Pa at 20-25℃
storage temp.  room temp
solubility  Acetone (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)
form  solid
color  white to off-white
Stability: Hygroscopic

Safety information for (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride

Computed Descriptors for (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride

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