(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
Synonym(s):(−)-(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol hydrochloride;(−)-N 0437;N 0923;Neupro;SPM 962
- CAS NO.:125572-93-2
- Empirical Formula: C19H26ClNOS
- Molecular Weight: 351.93
- EINECS: 603-080-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride?
Chemical properties
White to Off-White Solid
The Uses of (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.
What are the applications of Application
Rotigotine Hydrochloride is a D2DR and D3DR agonist
Biochem/physiol Actions
Rotigotine is a dopamine receptor agonist with preference for D3 receptors over D2 and D1. As such, it is an effective anti-Parkinsonian agent. Racemic rotigotine is about 50 times as potent as quinpirole, the gold standard D2 agonist.
storage
room temperature (desiccate)
Properties of (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
Melting point: | 114-117°C |
Density | 1.2g/cm3 at 20℃ |
vapor pressure | 0-0Pa at 20-25℃ |
storage temp. | room temp |
solubility | Acetone (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly) |
form | solid |
color | white to off-white |
Stability: | Hygroscopic |
Safety information for (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
Computed Descriptors for (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
2-NAPHTHALENAMINE, 1,2,3,4-TETRAHYDRO-N-METHYL-N-PROPYL-, HYDROCHLORIDE
ROTIGOTINE
Thiophene-2-ethylamine
(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
METHYL-(2-THIOPHEN-2-YL-ETHYL)-AMINE HYDROCHLORIDE
1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-
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