(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
Synonym(s):(−)-(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol hydrochloride;(−)-N 0437;N 0923;Neupro;SPM 962
- CAS NO.:125572-93-2
- Empirical Formula: C19H26ClNOS
- Molecular Weight: 351.93
- EINECS: 603-080-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-14 15:25:22
What is (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride?
Chemical properties
White to Off-White Solid
The Uses of (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.
What are the applications of Application
Rotigotine Hydrochloride is a D2DR and D3DR agonist
Biochem/physiol Actions
Rotigotine is a dopamine receptor agonist with preference for D3 receptors over D2 and D1. As such, it is an effective anti-Parkinsonian agent. Racemic rotigotine is about 50 times as potent as quinpirole, the gold standard D2 agonist.
storage
room temperature (desiccate)
Properties of (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
Melting point: | 114-117°C |
Density | 1.2g/cm3 at 20℃ |
vapor pressure | 0-0Pa at 20-25℃ |
storage temp. | room temp |
solubility | Acetone (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly) |
form | solid |
color | white to off-white |
Stability: | Hygroscopic |
Safety information for (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
Computed Descriptors for (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Rimegepant Impurity 3 Ivermectin EP Impurity B Tubulysin G Tubulysin E Tubulysin B Tubulysin D Potassium HMDS (1.0 M in THF) 2-chloro-6-methyl-4-nitropyridine 1-oxide 6-bromo-5-methoxypicolinic acid 2,3-Dibromo-5,6-dimethylpyridine quinuclidine-2-carboxylicacid HCl 2-fluoro-5-(Methylsurfonyl)benzoic acid 2-chloro-4-fluoro-5-Iodobenzophenon Calcium Sodium Phosphosilicate IH Imeglimin Hydrochloride IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Fuel shell 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 4,8-dibromo-5H-[1,2,3]triazolo[4',5':4,5]benzo[1,2-c][1,2,5]thiadiazole (1-Isopropyl-1H-pyrazol-5-yl)boronic acidRelated products of tetrahydrofuran
2-NAPHTHALENAMINE, 1,2,3,4-TETRAHYDRO-N-METHYL-N-PROPYL-, HYDROCHLORIDE
ROTIGOTINE
Thiophene-2-ethylamine
(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
METHYL-(2-THIOPHEN-2-YL-ETHYL)-AMINE HYDROCHLORIDE
1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-
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