6,7,8-TRIMETHOXYCOUMARIN
- CAS NO.：6035-49-0
- Empirical Formula: C12H12O5
- Molecular Weight: 236.22
- MDL number: MFCD00145039
- EINECS: 200-485-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-19 17:28:17
What is 6,7,8-TRIMETHOXYCOUMARIN?
Chemical properties
White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Fraxinuschinensis Roxb.
The Uses of 6,7,8-TRIMETHOXYCOUMARIN
Dimethylfraxetin has a bactericidal, anti-inflammatory, anti-radiation damage, and immune-enhancing effects.
Definition
ChEBI: 6,7,8-trimethoxy-1-benzopyran-2-one is a member of coumarins.
Biological Activity
Dimethylfraxetin is a Carbonic anhydrase inhibitor with a Ki of 0.0097 μM.
in vitro
At CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study .
Properties of 6,7,8-TRIMETHOXYCOUMARIN
| Melting point: | 104-105°C |
| Boiling point: | 338.68°C (rough estimate) |
| Density | 1.249 |
| refractive index | 1.5140 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO : 125 mg/mL (529.17 mM; Need ultrasonic and warming) |
| form | Cryst. |
| color | White to yellow |
Safety information for 6,7,8-TRIMETHOXYCOUMARIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for 6,7,8-TRIMETHOXYCOUMARIN
New Products
Indole Methyl Resin tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Boc-His(Boc)-OH 2-CTC Resin 4-Chloro-7-tosy1-7Hpyrrolo[2,3-d]pyrimidine 5,7-Dibromo-1H-indole 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidamide 2,2-Dimethoxy-7-azaspiro[3.5]nonane hydrochloride 4-chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl) R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDIIMIDAZOLE 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID 4-((2-hydroxyethyl)thio)benzoic acid 1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE Methyl 6-methylnicotinate 3-Pyridineacrylic acid tert-Butyl carbazate TETRAHYDRO-2H-PYRAN-3-OL 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile 2,4-dihydroxybenzaldehyde 1,3-Diethyl-1,3-Diphenylurea Methyl 2-methylquinoline-6-carboxylateRelated products of tetrahydrofuran
You may like
-
Pyridine 99.5% HPLC /UV SpectroscopyView Details
110-86-1 -
Guanine , 99%View Details
73-40-5 -
Piperazine Spot supply, best priceView Details
110-85-0 -
Potassium Hydroxide 90%View Details
1310-58-3 -
Dibutyl PhthalateView Details
84-74-2 -
Imidazole Spot supply, competitive priceView Details
288-32-4 -
Octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate 98% (GC)View Details
2082-79-3 -
Thiourea 99% ARView Details
62-56-6
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.