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HomeProduct name list6,6'-DITHIODINICOTINIC ACID

6,6'-DITHIODINICOTINIC ACID

Synonym(s):Bis[3-carboxypyridine] 6,6′-disulfide

  • CAS NO.:15658-35-2
  • Empirical Formula: C12H8N2O4S2
  • Molecular Weight: 308.33
  • MDL number: MFCD00006454
  • EINECS: 239-729-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 20:33:22
6,6'-DITHIODINICOTINIC ACID Structural

What is 6,6'-DITHIODINICOTINIC ACID?

Chemical properties

tan powder

The Uses of 6,6'-DITHIODINICOTINIC ACID

6,6′-Dithiodinicotinic acid may be employed as:

  • specific thiol blocker to investigate the radioprotective effect of mercaptoethylamine on the thiol level of the outer cell membrane of the Ehrlich ascites tumor cells
  • modifier to investigate the polar microenvironment around the reactive Cys283 of rabbit muscle creatine kinase
  • dipyridyl-dithio substrate to evaluate the protein disulfide-thiol interchange activity of the auxin stimulated NADH: protein disulfide reductase (NADH oxidase) of soybean plasma membranes
  • water-soluble reagent in a study for introducing, in buffered saline, a reactive sulfhydryl group on water-soluble molecules bearing an alkyl-amino group
  • chromogen for sulfhydryl groups in the Ellman method for cholinesterase determinations
  • spectrophotometric determination of thiols and of total glutathione in human blood

General Description

6,6′-Dithiodinicotinic acid is reported as sulphydryl reagent. 6,6′-Dithiodinicotinic acid is reported to react with thiols, to afford a disulfide and 6-mercaptonicotinic acid. Interaction of 6,6′-dithiodinicotinic acid with the homogenates of Ehrlich ascites cells has been reported.

Properties of 6,6'-DITHIODINICOTINIC ACID

Melting point: 263-265 °C(lit.)
Boiling point: 584.2±50.0 °C(Predicted)
Density  1.66±0.1 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
form  powder to crystal
pka 2.82±0.10(Predicted)
color  White to Light yellow
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 15658-35-2(CAS DataBase Reference)

Safety information for 6,6'-DITHIODINICOTINIC ACID

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 6,6'-DITHIODINICOTINIC ACID

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