(1R)-(-)-Nopol

Synonym(s):(−)-Nopol;(1R)-6,6-Dimethylbicyclo[3.1.1]hept-2-ene-2-ethanol;6,6-Dimethyl-2-norpinene-2-ethanol;6,6-Dimethylbicyclo[3.1.1]hept-2-ene-2-ethanol

CAS NO.：35836-73-8
Empirical Formula: C11H18O
Molecular Weight: 166.26
MDL number: MFCD00075187
EINECS: 252-744-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-06-07 16:07:22

What is (1R)-(-)-Nopol?

Chemical properties

Clear colorless to light yellow liquid

The Uses of (1R)-(-)-Nopol

(-)-Nopol, is a chiral building block used in chemical synthesis. It is an intermediate that can be used for the synthesis of bulky moiety-modified analogs to the sandalwood odorant Polysantol.

Definition

ChEBI: (-)-Nopol is a monoterpenoid.

What are the applications of Application

(1R)-(-)-Nopol may be used in the preparation of optically active O,O-diterpenyl dithiophosphoric and O-terpenyl aryldithiophosphonic acids by reacting with tetraphosphorus decasulfide and 2,4-diaryl 1,3,2,4-dithiadiphosphetane-2,4-disulfides, respectively. It may also react with silver hexafluoroantimonate to form a complex, which can be an effective initiator for the nonthermal curing of epoxy resins by electron beam induced cationic polymerization.

General Description

(1R)-(-)-Nopol is a chiral terpenol derivative.

Properties of (1R)-(-)-Nopol

Boiling point:	235-236 °C(lit.)
Density	0.973 g/mL at 25 °C(lit.)
vapor pressure	2.17Pa at 20℃
refractive index	n20/D 1.493
Flash point:	210 °F
storage temp.	Refrigerator, under inert atmosphere
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Oil
pka	15.03±0.10(Predicted)
color	Clear Colourless
optical activity	[α]24/D 37°, neat
Water Solubility	333.5mg/L at 20℃
Merck	14,6683
BRN	3196379

Safety information for (1R)-(-)-Nopol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.