(1R)-(+)-ALPHA-PINENE
Synonym(s):(+)-α-Pinene;(1R,5R)-2,6,6-Trimethylbicyclo[3.1.1]hept-2-ene;(1R,5R)-2-Pinene;(1R)-(+)-α-Pinene;(1R)-2,6,6-Trimethylbicyclo[3.1.1]hept-2-ene
- CAS NO.:7785-70-8
- Empirical Formula: C10H16
- Molecular Weight: 136.23
- MDL number: MFCD00001346
- EINECS: 232-087-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-11-17 15:41:33
What is (1R)-(+)-ALPHA-PINENE?
Chemical properties
(1R)-(+)-ALPHA-PINENE is Clear colourless liquid
The Uses of (1R)-(+)-ALPHA-PINENE
(1R)-(+)-α-Pinene is used in hydroboration reactions and the reduction of ketones.
The Uses of (1R)-(+)-ALPHA-PINENE
(+)-alpha-Pinene is employed in the preparation of chiral hydroboration reagents. It is a bronchodilator in humans. α-Pinene is an anti-inflammatory and used as a broad-spectrum antibiotic.It exhibits activity as an acetylcholinesterase inhibitor, aiding memory. It is a biosynthetic base for CB2 ligands, such as HU-308.
The Uses of (1R)-(+)-ALPHA-PINENE
(+)-α-Pinene has been used in a tolerance testing procedure to detect the genes in Marinobacter aquaeolei, for engineering a pinene tolerant Escherichia coli.
What are the applications of Application
(+)-α-Pinene is employed in the preparation of chiral hydroboration reagents
Definition
ChEBI: The (+)-enantiomer of alpha-pinene.
General Description
(+)-α-Pinene is a monoterpenoid compound mainly found in Pinus species.
Flammability and Explosibility
Flammable
Purification Methods
(1R)-(+)-ALPHA-PINENE is isomerised by heat, acids and certain solvents. It should be distilled under reduced pressure under nitrogen and stored in the dark. It has been purified via the nitrosochloride [Waterman et al. Recl Trav Chim, Pays-Bas 48 1191 1929]. For purification of optically active forms see Lynn [J Am Chem Soc 91 361 1919].
Properties of (1R)-(+)-ALPHA-PINENE
| Melting point: | −62 °C(lit.) |
| Boiling point: | 155-156 °C(lit.) |
| Density | 0.858 g/mL at 20 °C(lit.) |
| vapor pressure | 5 hPa (25 °C) |
| FEMA | 2902 | ALPHA-PINENE |
| refractive index | n |
| Flash point: | 91 °F |
| storage temp. | Store at +2°C to +8°C. |
| form | Liquid |
| color | Clear colorless |
| Odor | at 10.00 % in dipropylene glycol. harsh terpene aromatic minty |
| explosive limit | 0.8-6%(V) |
| optical activity | [α]22/D +47.1°, neat |
| Water Solubility | Soluble in Ether, Alcohols, Chloroform. Not miscible in water. |
| JECFA Number | 1329 |
| Merck | 14,7445 |
| BRN | 3648264 |
| Dielectric constant | 2.7(20℃) |
| CAS DataBase Reference | 7785-70-8(CAS DataBase Reference) |
| EPA Substance Registry System | Bicyclo[3.1.1]hept-2-ene, 2,6,6-trimethyl-, (1R,5R)- (7785-70-8) |
Safety information for (1R)-(+)-ALPHA-PINENE
| Signal word | Danger |
| Pictogram(s) |
![]() Flame Flammables GHS02 ![]() Exclamation Mark Irritant GHS07 ![]() Health Hazard GHS08 ![]() Environment GHS09 |
| GHS Hazard Statements |
H226:Flammable liquids H304:Aspiration hazard H315:Skin corrosion/irritation H317:Sensitisation, Skin H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for (1R)-(+)-ALPHA-PINENE
| InChIKey | GRWFGVWFFZKLTI-UHFFFAOYSA-N |
(1R)-(+)-ALPHA-PINENE manufacturer
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