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HomeProduct name list6-Methoxyquinoline

6-Methoxyquinoline

Synonym(s):6-Methoxyquinoline

  • CAS NO.:5263-87-6
  • Empirical Formula: C10H9NO
  • Molecular Weight: 159.18
  • MDL number: MFCD00006800
  • EINECS: 226-077-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-31 13:32:20
6-Methoxyquinoline Structural

What is 6-Methoxyquinoline?

Chemical properties

colorless to light yellow liquid

The Uses of 6-Methoxyquinoline

6-Methoxyquinoline is a useful sythetic intermediate

The Uses of 6-Methoxyquinoline

6-Methoxyquinoline is used as a precursor in the synthesis of:

  • Fluorescent zinc and chlorine sensors.
  • 5-Amino-2-aroylquinolines as potent tubulin polymerization inhibitors.
  • 3-Fluoro-6-methoxyquinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase.
  • Cobalt-based ternary metal-organic complex as single?ion magnets.

What are the applications of Application

6-Methoxyquinoline is A useful sythetic intermediate

Definition

ChEBI: An aromatic ether that is quinoline substituted at position 6 by a methoxy group.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1584, 1946 DOI: 10.1021/ja01212a062

Properties of 6-Methoxyquinoline

Melting point: 18-20 °C (lit.)
Boiling point: 140-146 °C/15 mmHg (lit.)
Density  1.15 g/mL at 20 °C (lit.)
refractive index  n20/D 1.625(lit.)
FEMA  4640 | 6-METHOXYQUINOLINE
Flash point: >230 °F
storage temp.  Store below +30°C.
solubility  soluble in Alcohol
pka 5.03(at 20℃)
form  Granular Powder
color  White to cream
Odor heavy sweet
Water Solubility  insoluble
Sensitive  Light Sensitive
JECFA Number 2157
BRN  115244
CAS DataBase Reference 5263-87-6(CAS DataBase Reference)
NIST Chemistry Reference Quinoline, 6-methoxy-(5263-87-6)
EPA Substance Registry System Quinoline, 6-methoxy- (5263-87-6)

Safety information for 6-Methoxyquinoline

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for 6-Methoxyquinoline

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