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HomeProduct name list6-HYDROXYCHLORZOXAZONE

6-HYDROXYCHLORZOXAZONE

Synonym(s):5-Chloro-6-hydroxy-2(3H)-benzoxazolone;5-Chloro-6-hydroxybenzoxazone

  • CAS NO.:1750-45-4
  • Empirical Formula: C7H4ClNO3
  • Molecular Weight: 185.56
  • MDL number: MFCD00143502
  • EINECS: 621-147-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-23 13:36:13
6-HYDROXYCHLORZOXAZONE Structural

What is 6-HYDROXYCHLORZOXAZONE?

Chemical properties

Off-White Solid

The Uses of 6-HYDROXYCHLORZOXAZONE

6-Hydroxychlorzoxazone has been used for HPLC-based metabolic assays of chlorzoxazone.

The Uses of 6-HYDROXYCHLORZOXAZONE

A major metabolite of chlorzoxazone. Formed by the actions of cytochrome P450IIE1

What are the applications of Application

6-Hydroxy chlorzoxazone is a major metabolite of chlorzoxazone

Definition

ChEBI: 6-Hydroxychlorzoxazone is a benzoxazole.

Biochem/physiol Actions

6-hydroxy Chlorzoxazone is a novel metabolite of chlorzoxazone. It is formed by the hydroxylation of chlorzoxazone by cytochrome P450 family 2 subfamily E member 1 (CYP2E1) enzyme. The determination of formation and clearance of 6-hydroxychlorzoxazone is used as a reliable marker of CYP2E1 metabolic activity.

Properties of 6-HYDROXYCHLORZOXAZONE

Melting point: 240-242°C
Density  1.649±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  methanol: soluble
form  Solid
pka 7.83±0.70(Predicted)
color  white to pink
CAS DataBase Reference 1750-45-4

Safety information for 6-HYDROXYCHLORZOXAZONE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 6-HYDROXYCHLORZOXAZONE

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