6-aminotetralin-2,3-diol
Synonym(s):6,7-ADTN hydrobromide
- CAS NO.:13575-86-5
- Empirical Formula: C10H13NO2
- Molecular Weight: 0
- MDL number: MFCD00036982
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-21 08:27:59
What is 6-aminotetralin-2,3-diol?
Description
6,7-ADTN HBr (13575-86-5) is a broad spectrum dopamine receptor agonist.1,2? Demonstrates a marked selectivity for the human dopamine D3 receptor.3 6,7-ADTN and psychostimulants such as cocaine and amphetamine reduce excitatory synaptic transmission in the nucleus accumbens by activating presynaptic dopamine receptors.4
The Uses of 6-aminotetralin-2,3-diol
(+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide is a dopamine receptor agonist in Tribolium castaneum.
What are the applications of Application
6,7-ADTN hydrobromide is a dopamine receptor agonist
References
1) List et al. (1982), Striatal binding of 2-amino-6,7-[3H]dihydroxy-1,2,3,4-tetrahydronaphthalene to two dopaminergic sites distinguished by their low and high affinity for neuroleptics; J. Neurosci., 2 895 2) Templeton et al. (1982), Binding of [3H]ADTN to rat striatal membranes; Biochem. Pharmacol., 31 1629 3) Freedman et al. (1994), Expression and pharmacological characterization of the human D3 dopamine receptor; Curr. J. Pharmacol. Exp. Ther., 268 417 4) Nicola et al. (1996), Psychostimulants depress excitatory synaptic transmission in the nucleus accumbens via presynaptic D1-like dopamine receptors; J. Neurosci., 16 1591
Properties of 6-aminotetralin-2,3-diol
Melting point: | 270-271 °C |
storage temp. | 2-8°C |
solubility | Soluble in Water (up to 25 mg/ml) |
form | solid |
color | Tan |
Stability: | Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 week. |
Safety information for 6-aminotetralin-2,3-diol
Computed Descriptors for 6-aminotetralin-2,3-diol
New Products
Tubulysin H Tubulysin D Tubulysin A Tubulysin B 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 3-Aminocyclobutanone hydrochloride 2,2-Difluoropropylamine hydrochloride 3-METHYLAZETIDIN-3-OL HYDROCHLORIDE 1-(1,1-Difluoroethyl)-2-fluorobenzene 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Calcium Sodium Phosphosilicate IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Imeglimin Hydrochloride IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Latanoprostene Bunod Magnesium Trisilicate Lubiprostone Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
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