5,7-DIBROMO-8-HYDROXYQUINOLINE

CAS NO.：521-74-4
Empirical Formula: C9H5Br2NO
Molecular Weight: 302.95
MDL number: MFCD00006785
EINECS: 208-317-8
SAFETY DATA SHEET (SDS)
Update Date: 2024-12-18 14:15:30

What is 5,7-DIBROMO-8-HYDROXYQUINOLINE?

Chemical properties

almost white powder

Originator

Brodiar,Intervet

The Uses of 5,7-DIBROMO-8-HYDROXYQUINOLINE

antiinfectant, disinfectant

The Uses of 5,7-DIBROMO-8-HYDROXYQUINOLINE

In testing for Cu, Fe, Ti.

The Uses of 5,7-DIBROMO-8-HYDROXYQUINOLINE

5,7-Dibromoquinolin-8-ol

Definition

ChEBI: 5,7-dibromo-8-quinolinol is a member of quinolines and an organohalogen compound.

Manufacturing Process

To a suspension of 14.5 g of 8-hydroxyquinoline in 400 ml of water was added dropwise a solution of 32.3 g bromine and 30 g 8% aqueous hydrobromide in 30 ml water. A temperature of reaction mixture decreased to 33°C. Stirring was continued for 30 min, a fine yellow 5,7-dibromo-8-hydroxyquinoline was collected by filtration, washed with water and dried; yield 29.8 g (98.4%), melting point 201°C.

brand name

Aprilin;Auanosept;Dibromoksin;Dibromoquin;Dibromoxine;Digesept;Diromo;Dirorno;Dysentrocym;Enosept;Enterokvin;Intestopan-q;Noroquinol;Paramibrodiar;Phenipan;Sandocycline;Sandoin;Starogyn;Susiform ad is vet.

Therapeutic Function

Antibacterial

World Health Organization (WHO)

Broxyquinoline is a halogenated hydroxyquinoline. See entry for halogenated hydroxyquinoline derivatives and WHO comment for clioquinol.

Purification Methods

Crystallise it from acetone/EtOH. It can be sublimed. [Beilstein 21/3 V 290.]

Properties of 5,7-DIBROMO-8-HYDROXYQUINOLINE

Melting point:	198-200 °C(lit.)
Boiling point:	363.74°C (rough estimate)
Density	2.189
refractive index	1.6400 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form	Solid
pka	2.23±0.30(Predicted)
color	Off-White to Pale Beige
Merck	14,1453
BRN	153624
CAS DataBase Reference	521-74-4(CAS DataBase Reference)
EPA Substance Registry System	Broxyquinoline (521-74-4)

Safety information for 5,7-DIBROMO-8-HYDROXYQUINOLINE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.