5,7-DIBROMO-8-HYDROXYQUINOLINE
- CAS NO.:521-74-4
- Empirical Formula: C9H5Br2NO
- Molecular Weight: 302.95
- MDL number: MFCD00006785
- EINECS: 208-317-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-04 20:04:50
What is 5,7-DIBROMO-8-HYDROXYQUINOLINE?
Chemical properties
almost white powder
Originator
Brodiar,Intervet
The Uses of 5,7-DIBROMO-8-HYDROXYQUINOLINE
antiinfectant, disinfectant
The Uses of 5,7-DIBROMO-8-HYDROXYQUINOLINE
In testing for Cu, Fe, Ti.
The Uses of 5,7-DIBROMO-8-HYDROXYQUINOLINE
5,7-Dibromoquinolin-8-ol
Definition
ChEBI: 5,7-dibromo-8-quinolinol is a member of quinolines and an organohalogen compound.
Manufacturing Process
To a suspension of 14.5 g of 8-hydroxyquinoline in 400 ml of water was added dropwise a solution of 32.3 g bromine and 30 g 8% aqueous hydrobromide in 30 ml water. A temperature of reaction mixture decreased to 33°C. Stirring was continued for 30 min, a fine yellow 5,7-dibromo-8-hydroxyquinoline was collected by filtration, washed with water and dried; yield 29.8 g (98.4%), melting point 201°C.
brand name
Aprilin;Auanosept;Dibromoksin;Dibromoquin;Dibromoxine;Digesept;Diromo;Dirorno;Dysentrocym;Enosept;Enterokvin;Intestopan-q;Noroquinol;Paramibrodiar;Phenipan;Sandocycline;Sandoin;Starogyn;Susiform ad is vet.
Therapeutic Function
Antibacterial
World Health Organization (WHO)
Broxyquinoline is a halogenated hydroxyquinoline. See entry for halogenated hydroxyquinoline derivatives and WHO comment for clioquinol.
Purification Methods
Crystallise it from acetone/EtOH. It can be sublimed. [Beilstein 21/3 V 290.]
Properties of 5,7-DIBROMO-8-HYDROXYQUINOLINE
Melting point: | 198-200 °C(lit.) |
Boiling point: | 363.74°C (rough estimate) |
Density | 2.189 |
refractive index | 1.6400 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated) |
form | Solid |
pka | 2.23±0.30(Predicted) |
color | Off-White to Pale Beige |
Merck | 14,1453 |
BRN | 153624 |
CAS DataBase Reference | 521-74-4(CAS DataBase Reference) |
EPA Substance Registry System | Broxyquinoline (521-74-4) |
Safety information for 5,7-DIBROMO-8-HYDROXYQUINOLINE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 5,7-DIBROMO-8-HYDROXYQUINOLINE
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
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