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HomeProduct name list5,7-DIBROMO-8-HYDROXYQUINOLINE

5,7-DIBROMO-8-HYDROXYQUINOLINE

  • CAS NO.:521-74-4
  • Empirical Formula: C9H5Br2NO
  • Molecular Weight: 302.95
  • MDL number: MFCD00006785
  • EINECS: 208-317-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 20:33:22
5,7-DIBROMO-8-HYDROXYQUINOLINE Structural

What is 5,7-DIBROMO-8-HYDROXYQUINOLINE?

Chemical properties

almost white powder

Originator

Brodiar,Intervet

The Uses of 5,7-DIBROMO-8-HYDROXYQUINOLINE

antiinfectant, disinfectant

The Uses of 5,7-DIBROMO-8-HYDROXYQUINOLINE

In testing for Cu, Fe, Ti.

The Uses of 5,7-DIBROMO-8-HYDROXYQUINOLINE

5,7-Dibromoquinolin-8-ol

Definition

ChEBI: 5,7-dibromo-8-quinolinol is a member of quinolines and an organohalogen compound.

Manufacturing Process

To a suspension of 14.5 g of 8-hydroxyquinoline in 400 ml of water was added dropwise a solution of 32.3 g bromine and 30 g 8% aqueous hydrobromide in 30 ml water. A temperature of reaction mixture decreased to 33°C. Stirring was continued for 30 min, a fine yellow 5,7-dibromo-8-hydroxyquinoline was collected by filtration, washed with water and dried; yield 29.8 g (98.4%), melting point 201°C.

brand name

Aprilin;Auanosept;Dibromoksin;Dibromoquin;Dibromoxine;Digesept;Diromo;Dirorno;Dysentrocym;Enosept;Enterokvin;Intestopan-q;Noroquinol;Paramibrodiar;Phenipan;Sandocycline;Sandoin;Starogyn;Susiform ad is vet.

Therapeutic Function

Antibacterial

World Health Organization (WHO)

Broxyquinoline is a halogenated hydroxyquinoline. See entry for halogenated hydroxyquinoline derivatives and WHO comment for clioquinol.

Purification Methods

Crystallise it from acetone/EtOH. It can be sublimed. [Beilstein 21/3 V 290.]

Properties of 5,7-DIBROMO-8-HYDROXYQUINOLINE

Melting point: 198-200 °C(lit.)
Boiling point: 363.74°C (rough estimate)
Density  2.189
refractive index  1.6400 (estimate)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form  Solid
pka 2.23±0.30(Predicted)
color  Off-White to Pale Beige
Merck  14,1453
BRN  153624
CAS DataBase Reference 521-74-4(CAS DataBase Reference)
EPA Substance Registry System Broxyquinoline (521-74-4)

Safety information for 5,7-DIBROMO-8-HYDROXYQUINOLINE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for 5,7-DIBROMO-8-HYDROXYQUINOLINE

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