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HomeProduct name list5,2'-O-Dimethyluridine

5,2'-O-Dimethyluridine

  • CAS NO.:55486-09-4
  • Empirical Formula: C11H16N2O6
  • Molecular Weight: 272.25
  • MDL number: MFCD03788700
  • EINECS: 2017-001-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-28 23:16:16
5,2'-O-Dimethyluridine Structural

What is 5,2'-O-Dimethyluridine?

Description

5-Me-2'-OMe Uridine is one of three oligonucleotide in platinum-derivatized homopyrimidine triplex-forming oligonucleotides (Pt-TFOs) useful in crosslinking to the transcribed strand in the human androgen receptor (AR) gene. Inhibitory activity against M. bovis and M. avium.

The Uses of 5,2'-O-Dimethyluridine

5-Methyl-2’-O-methyluridine is one of three oligonucleotide in platinum-derivatized homopyrimidine triplex-forming oligonucleotides (Pt-TFOs) useful in crosslinking to the transcribed strand in the human androgen receptor (AR) gene. Inhibitory activity against M. bovis and M. avium.

Definition

ChEBI: A methyluridine that consists of uridine bearing two methyl substituents located at position C-5 on the uracil ring and position O-2' on the ribose ring.

Properties of 5,2'-O-Dimethyluridine

Melting point: 183-186°C
Density  1.47±0.1 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  DMSO (Slightly), Methanol (Slightly, Sonicated)
pka 9.55±0.10(Predicted)
form  Solid
color  White to Off-White
CAS DataBase Reference 55486-09-4(CAS DataBase Reference)

Safety information for 5,2'-O-Dimethyluridine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 5,2'-O-Dimethyluridine

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