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HomeProduct name list5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

Synonym(s):Bz-DMT-dC

  • CAS NO.:67219-55-0
  • Empirical Formula: C37H35N3O7
  • Molecular Weight: 633.69
  • MDL number: MFCD00010114
  • EINECS: 266-605-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-06-08 09:03:02
5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine Structural

What is 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine?

Chemical properties

Off-white powder

The Uses of 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

5''-O-(4,4''-Dimethoxytrityl)-N4-benzoyl-2''-deoxycytidine (CAS# 67219-55-0) is a cytidine nucleoside derivative, and has been used as a reactant with synthetic modified DNA and RNA, such as in the site-selective RNA activation by acridine-modified oligodeoxynucleotides in metal-ion catalyzed hydrolysis.

The Uses of 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

N4-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine has been used as research tool for anti-viral and anti-cancer studies.

General Description

The 3′-O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite derivatives of N4-benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine (DMT-dCBz) participates in Diels-Alder reaction between diene-modified oligonucleotides and maleimide-derivatized peptides.

Flammability and Explosibility

Not classified

Properties of 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

Melting point: 119 °C
Boiling point: 668.71°C (rough estimate)
Density  1.2234 (rough estimate)
refractive index  58 ° (C=1, MeOH)
storage temp.  2-8°C
solubility  DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
form  powder to crystaline
pka 8.67±0.20(Predicted)
color  White to Almost white
Water Solubility  100μg/L at 20℃
BRN  601627
CAS DataBase Reference 67219-55-0(CAS DataBase Reference)
EPA Substance Registry System Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy- (67219-55-0)

Safety information for 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H319:Serious eye damage/eye irritation
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P391:Collect spillage. Hazardous to the aquatic environment
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

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