5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

Synonym(s):Bz-DMT-dC

CAS NO.：67219-55-0
Empirical Formula: C37H35N3O7
Molecular Weight: 633.69
MDL number: MFCD00010114
EINECS: 266-605-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-28 23:16:16

5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine Structural

What is 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine?

Chemical properties

Off-white powder

The Uses of 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

5''-O-(4,4''-Dimethoxytrityl)-N4-benzoyl-2''-deoxycytidine (CAS# 67219-55-0) is a cytidine nucleoside derivative, and has been used as a reactant with synthetic modified DNA and RNA, such as in the site-selective RNA activation by acridine-modified oligodeoxynucleotides in metal-ion catalyzed hydrolysis.

The Uses of 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

N⁴-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine has been used as research tool for anti-viral and anti-cancer studies.

General Description

The 3′-O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite derivatives of N⁴-benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine (DMT-dC^Bz) participates in Diels-Alder reaction between diene-modified oligonucleotides and maleimide-derivatized peptides.

Flammability and Explosibility

Not classified

Properties of 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

Melting point:	119 °C
Boiling point:	668.71°C (rough estimate)
Density	1.2234 (rough estimate)
refractive index	58 ° (C=1, MeOH)
storage temp.	2-8°C
solubility	DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
form	powder to crystaline
pka	8.67±0.20(Predicted)
color	White to Almost white
Water Solubility	100μg/L at 20℃
BRN	601627
CAS DataBase Reference	67219-55-0(CAS DataBase Reference)
EPA Substance Registry System	Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy- (67219-55-0)

Safety information for 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H319:Serious eye damage/eye irritation H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P391:Collect spillage. Hazardous to the aquatic environment P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention.