5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
Synonym(s):Bz-DMT-dC
- CAS NO.：67219-55-0
- Empirical Formula: C37H35N3O7
- Molecular Weight: 633.69
- MDL number: MFCD00010114
- EINECS: 266-605-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine?
Chemical properties
Off-white powder
The Uses of 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
5''-O-(4,4''-Dimethoxytrityl)-N4-benzoyl-2''-deoxycytidine (CAS# 67219-55-0) is a cytidine nucleoside derivative, and has been used as a reactant with synthetic modified DNA and RNA, such as in the site-selective RNA activation by acridine-modified oligodeoxynucleotides in metal-ion catalyzed hydrolysis.
The Uses of 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
N4-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine has been used as research tool for anti-viral and anti-cancer studies.
General Description
The 3′-O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite derivatives of N4-benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine (DMT-dCBz) participates in Diels-Alder reaction between diene-modified oligonucleotides and maleimide-derivatized peptides.
Flammability and Explosibility
Not classified
Properties of 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
| Melting point: | 119 °C |
| Boiling point: | 668.71°C (rough estimate) |
| Density | 1.2234 (rough estimate) |
| refractive index | 58 ° (C=1, MeOH) |
| storage temp. | 2-8°C |
| solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml |
| form | powder to crystaline |
| pka | 8.67±0.20(Predicted) |
| color | White to Almost white |
| Water Solubility | 100μg/L at 20℃ |
| BRN | 601627 |
| CAS DataBase Reference | 67219-55-0(CAS DataBase Reference) |
| EPA Substance Registry System | Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy- (67219-55-0) |
Safety information for 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P391:Collect spillage. Hazardous to the aquatic environment P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
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