5-Nitroindole
Synonym(s):NSC 520594
- CAS NO.:6146-52-7
- Empirical Formula: C8H6N2O2
- Molecular Weight: 162.15
- MDL number: MFCD00005673
- EINECS: 228-153-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is 5-Nitroindole?
Chemical properties
Yellow-Green Cyrstalline Solid
The Uses of 5-Nitroindole
Reactant for preparation of:• ;Pharmaceutically active 2-oxo-1-pyrrolidine analogues1• ;Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• ;Protein Kinase Inhibitors and antiproliferative agents3• ;Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4)4• ;Antifungal agents5• ;Cannabinoid receptor type 1 (CB1) antagonists6• ;Potential anticancer agents7• ;Potential antivascular agents8• ;Selective Anti-leukemic agents9• ;Anti human immunodeficiency virus subtype 1 (
The Uses of 5-Nitroindole
5-Nitroindole (cas# 6146-52-7) is a compound useful in organic synthesis.
The Uses of 5-Nitroindole
Reactant for preparation of:
- Pharmaceutically active 2-oxo-1-pyrrolidine analogues
- Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
- Protein Kinase Inhibitors and antiproliferative agents
- Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4)
- Antifungal agents
- Cannabinoid receptor type 1 (CB1) antagonists
- Potential anticancer agents
- Potential antivascular agents
- Selective Anti-leukemic agents
- Anti human immunodeficiency virus subtype 1 (HIV-1) agents
Purification Methods
Decolourise (charcoal) 5-nitroindole and recrystallise it twice from aqueous EtOH or recrystallise it from octane. It has UV: 265 and 324nm (EtOH). [Beilstein 20 III/IV 3194, 20/7 V 41.]
Properties of 5-Nitroindole
Melting point: | 140-142 °C (lit.) |
Boiling point: | 288.82°C (rough estimate) |
Density | 1.3264 (rough estimate) |
refractive index | 1.5770 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Dichloromethane, Ethyl Acetate, Methanol |
form | Crystalline Powder or Needles |
pka | 15.25±0.30(Predicted) |
color | Yellow |
BRN | 383777 |
InChI | InChI=1S/C8H6N2O2/c11-10(12)7-1-2-8-6(5-7)3-4-9-8/h1-5,9H |
CAS DataBase Reference | 6146-52-7(CAS DataBase Reference) |
Safety information for 5-Nitroindole
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H318:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 5-Nitroindole
InChIKey | OZFPSOBLQZPIAV-UHFFFAOYSA-N |
SMILES | N1C2=C(C=C([N+]([O-])=O)C=C2)C=C1 |
Abamectin manufacturer
Sunlight Active Drug Ingredients Pvt ltd
Cefa-Cilinas Biotics Pvt Ltd
JSK Chemicals
Syn Finechem Laboratories Pvt Ltd.
Montage Chemicals Pvt Ltd
Mekong pharmaceuticals pvt ltd
S D Fine Chem Limited
BASR Fine Chemicals Pvt. Ltd.
New Products
Bromine 99.5% AR (4 x 500ml) Fehling's Solution No. B Amino Acid Kit of 23 items set Ammonium Molybdate Reagent Solution Beam's Reagent Solution Ehrlich's Reagent For detection of urobillinogen 4-((2-isopropoxyethoxy)methyl)phenol 4-Hydroxy Carbazole Amino Salicylic Acid. U.S.P. 2 – Methoxy – 5- Sulfamoyl Benzoic acid 1,2,3,4-Tetrahydrocarbazol-4-one Acetone Isobutryl oxime ester Curcuma aromatica Oil Curry leaf Extract Terminalia bellirica Extract Aloe vera extract 200x Withania somnifera (Ashwagandha Extract) Citrus bioflavonoids Extract Ethyl 3-(Pyridin-2-Ylamino)Propanoate Bilastine -IP/BP/ Cypermethric Acid Chloride Methyl Di Chloride (Mdc) 5-Nitrosalicylaldehyde 5-(Difluoromethoxy)-2-Mercapto-1H-Benzimidazole- IP/BP/Related products of tetrahydrofuran
You may like
-
5-Nitroindole 99%View Details
6146-52-7 -
5-Nitroindole 98%View Details
-
5-Nitroindole 99%View Details
6146-52-7 -
6146-52-7 5-Nitroindole 98%View Details
6146-52-7 -
5-Nitroindole CAS 6146-52-7View Details
6146-52-7 -
5-Nitroindole 98%View Details
6146-52-7 -
5-Nitro indole, 98% CAS 6146-52-7View Details
6146-52-7 -
5-Nitroindole CAS 6146-52-7View Details
6146-52-7