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HomeProduct name list5-Fluoro-1,3-isobenzofurandione

5-Fluoro-1,3-isobenzofurandione

  • CAS NO.:319-03-9
  • Empirical Formula: C8H3FO3
  • Molecular Weight: 166.11
  • MDL number: MFCD00191363
  • EINECS: 1312995-182-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
5-Fluoro-1,3-isobenzofurandione Structural

What is 5-Fluoro-1,3-isobenzofurandione?

Chemical properties

white to light yellow crystal powder

The Uses of 5-Fluoro-1,3-isobenzofurandione

4-Fluorophthalic anhydride is used in the preparation of 5-fluoro-2-pyridin-3-ylmethyl-isoindole-1,3-dione by reacting with C-pyridin-3-yl-methylamine.

The Uses of 5-Fluoro-1,3-isobenzofurandione

4-Fluorophthalic anhydride can be used as a reactant to prepare:

  • 4-amino substituted phthalimides applicable as potential fluorescent probes and fluorescent bioactive compounds.
  • 4,4′-bis(4-fluorophthalimido)diphenyl ether monomer, which is used in the synthesis of cardo polymers via nucleophilic substitution polymerization reaction.
  • Asymmetric polyimides by a solution polycondensation reaction.

General Description

4-Fluorophthalic anhydride is a fluorinated building block commonly used in chemical synthesis for the preparation of polyimide, pesticides, herbicides, and fungicides. It can be synthesized by treating 4-chlorophthalic anhydride with potassium fluoride.

Properties of 5-Fluoro-1,3-isobenzofurandione

Melting point: 75-79 °C (lit.)
Boiling point: 148°C 20mm
Density  1.55
Flash point: >93°C
storage temp.  Inert atmosphere,Store in freezer, under -20°C
solubility  Soluble in sodium hydroxide.
form  powder to crystal
color  White to Almost white
Sensitive  Moisture Sensitive
BRN  131281
CAS DataBase Reference 319-03-9(CAS DataBase Reference)
EPA Substance Registry System 1,3-Isobenzofurandione, 5-fluoro- (319-03-9)

Safety information for 5-Fluoro-1,3-isobenzofurandione

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 5-Fluoro-1,3-isobenzofurandione

InChIKey XVMKZAAFVWXIII-UHFFFAOYSA-N

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