5-Fluoro-1,3-isobenzofurandione

CAS NO.：319-03-9
Empirical Formula: C8H3FO3
Molecular Weight: 166.11
MDL number: MFCD00191363
EINECS: 1312995-182-4
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 5-Fluoro-1,3-isobenzofurandione?

Chemical properties

white to light yellow crystal powder

The Uses of 5-Fluoro-1,3-isobenzofurandione

4-Fluorophthalic anhydride is used in the preparation of 5-fluoro-2-pyridin-3-ylmethyl-isoindole-1,3-dione by reacting with C-pyridin-3-yl-methylamine.

The Uses of 5-Fluoro-1,3-isobenzofurandione

4-Fluorophthalic anhydride can be used as a reactant to prepare:

4-amino substituted phthalimides applicable as potential fluorescent probes and fluorescent bioactive compounds.
4,4′-bis(4-fluorophthalimido)diphenyl ether monomer, which is used in the synthesis of cardo polymers via nucleophilic substitution polymerization reaction.
Asymmetric polyimides by a solution polycondensation reaction.

General Description

4-Fluorophthalic anhydride is a fluorinated building block commonly used in chemical synthesis for the preparation of polyimide, pesticides, herbicides, and fungicides. It can be synthesized by treating 4-chlorophthalic anhydride with potassium fluoride.

Properties of 5-Fluoro-1,3-isobenzofurandione

Melting point:	75-79 °C (lit.)
Boiling point:	148°C 20mm
Density	1.55
Flash point:	>93°C
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	Soluble in sodium hydroxide.
form	powder to crystal
color	White to Almost white
Sensitive	Moisture Sensitive
BRN	131281
CAS DataBase Reference	319-03-9(CAS DataBase Reference)
EPA Substance Registry System	1,3-Isobenzofurandione, 5-fluoro- (319-03-9)

Safety information for 5-Fluoro-1,3-isobenzofurandione

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.