Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list5-Chloro-2-methylaniline

5-Chloro-2-methylaniline

Synonym(s):4-Chloro-2-toluidine, 5-Chloro-o-toluidine, 2-Amino-4-chlorotoluene;5-Chloro-2-methylaniline

  • CAS NO.:95-79-4
  • Empirical Formula: C7H8ClN
  • Molecular Weight: 141.6
  • MDL number: MFCD00007779
  • EINECS: 202-452-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-04 17:34:44
5-Chloro-2-methylaniline Structural

What is 5-Chloro-2-methylaniline?

Chemical properties

clear yellow to light brown liquid after melting

Chemical properties

The chloromethylanilines are colorless or white crystalline solids or liquids, some have a mild fishy odor.

The Uses of 5-Chloro-2-methylaniline

5-Chloro-2-toluidine, is a versatile building block used for the synthesis of various pharmaceutical and biologically active compounds including inhibitors. It is a carcinogenic monocyclic amine. The compound is used in synthesizing dyes.

Definition

ChEBI: 5-Chloro-ortho-toluidine is a member of monochlorobenzenes.

Potential Exposure

Most of the isomers are used in dyestuff manufacture. The 3-chloro-para isomer is used to kill birds. It is marketed as pelleted bait for control of bird populations.

Carcinogenicity

A bioassay for the possible carcinogenicity of 5-chloro-otoluidine was conducted using Fischer 344 rats and B6C3F1 mice. Groups of 50 male and 50 female rats and mice were given 5-chloro-o-toluidine in the diet at 2500 or 5000 ppm for rats and 2000 or 4000 ppm for mice. The compound was administered for 78 weeks to both rats and mice, followed by an observation period of up to 26 weeks for rats and 13 weeks for mice. Under the conditions of this bioassay, 5-chloro-otoluidine was carcinogenic to the mice, inducing hemangiosarcomas and hepatocellular carcinomas in both males and females. There was no conclusive evidence of the carcinogenicity of the compound in the rats.

Shipping

UN2239 Chlorotoluidines, solid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3429 Chlorotoluidines, liquid, Hazard Class: 6.1; Labels: 6.1- Poisonous materials

Incompatibilities

Incompatible with oxidizers, strong acids; chloroformates, and acid anhydrides, isocyanates, aldehydes forming fire and explosive hazards.

Properties of 5-Chloro-2-methylaniline

Melting point: 22 °C
Boiling point: 237 °C(lit.)
Density  1.177 g/mL at 20 °C(lit.)
vapor pressure  0.45 hPa (50 °C)
refractive index  n20/D 1.584(lit.)
Flash point: 320 °F
storage temp.  Store below +30°C.
solubility  soluble in Alcohol
form  Liquid After Melting
pka pK1:3.85(+1) (25°C)
color  Clear yellow to light brown
Water Solubility  < 1 g/L (22 ºC)
BRN  878504
CAS DataBase Reference 95-79-4(CAS DataBase Reference)
IARC 3 (Vol. 77, 99) 2010
NIST Chemistry Reference Benzenamine, 5-chloro-2-methyl-(95-79-4)
EPA Substance Registry System 5-Chloro-2-methylaniline (95-79-4)

Safety information for 5-Chloro-2-methylaniline

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 5-Chloro-2-methylaniline

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.