5-Bromo-2-chlorobenzoic acid

CAS NO.：21739-92-4
Empirical Formula: C7H4BrClO2
Molecular Weight: 235.46
MDL number: MFCD00002415
EINECS: 244-558-5
SAFETY DATA SHEET (SDS)
Update Date: 2025-02-13 18:31:58

What is 5-Bromo-2-chlorobenzoic acid ?

Chemical properties

white to light yellow crystal powder

The Uses of 5-Bromo-2-chlorobenzoic acid

5-Bromo-2-chlorobenzoic acid was used to evaluate the homogeneity of organic powder. It can be used to produce 2-chloro-5-deuteriobenzoic acid.

Description

The 5-bromo-2-chlorobenzoic acid is a common key intermediate for synthesizing a novel antidiabetic SGLT-2 inhibitor, which is a new-generation diabetes drug that controls blood sugar by inhibiting the reabsorption of glucose in the kidney.

Properties of 5-Bromo-2-chlorobenzoic acid

Melting point:	154-156 °C (lit.)
Boiling point:	324.5±27.0 °C(Predicted)
Density	1.7312 (rough estimate)
refractive index	1.5590 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	2.63g/l
form	Solid
pka	2.49±0.25(Predicted)
color	Off white colored powder
Water Solubility	Soluble in water 2.63 g/L @20°C.
BRN	2691432
InChI	InChI=1S/C7H4BrClO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,(H,10,11)
CAS DataBase Reference	21739-92-4(CAS DataBase Reference)
NIST Chemistry Reference	5-Bromo-2-chlorobenzoic acid(21739-92-4)
EPA Substance Registry System	Benzoic acid, 5-bromo-2-chloro- (21739-92-4)

Safety information for 5-Bromo-2-chlorobenzoic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.