SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
| Molecular Weight | 235.46 g/mol |
|---|---|
| XLogP3 | 2.9 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 233.90832 g/mol |
| Monoisotopic Mass | 233.90832 g/mol |
| Topological Polar Surface Area | 37.3 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 163 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
Description
5-Bromo-2-chlorobenzoic acid, with the chemical formula C7H4BrClO2, has the CAS number 21739-92-4. It appears as a white to off-white crystalline powder with no distinct odor. The basic structure of 5-Bromo-2-chlorobenzoic acid consists of a benzene ring with a bromine atom and a chlorine atom attached to it, as well as a carboxylic acid group. 5-bromo-2-chlorobenzoic acid is a common key intermediate for synthesizing a novel antidiabetic SGLT-2 inhibitor. SGLT-2 inhibitor is a new-generation diabetes drug that controls blood sugar by inhibiting the reabsorption of glucose in the kidney, has a unique action mechanism, does not depend on the dysfunction of beta cells or the degree of insulin resistance, has no effect reduction along with the function failure of the beta cells or serious insulin resistance, does not generate adverse reaction brought by the traditional drugs, has various clinical advantages.