5-ALPHA-ANDROSTANE
Synonym(s):Etioallocholane
- CAS NO.：438-22-2
- Empirical Formula: C19H32
- Molecular Weight: 260.46
- MDL number: MFCD00067600
- EINECS: 207-116-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:30
What is 5-ALPHA-ANDROSTANE?
The Uses of 5-ALPHA-ANDROSTANE
5alpha-Androstane is an anabolic steroid.
Definition
ChEBI: 5alpha-androstane is the 5alpha-stereoisomer of androstane. It has a role as a human metabolite.
Purification Methods
Purify 5-androstane by chromatography through Al2O3 (grade III) and elute with pet ether and recrystallise from MeOH (2x) and Me2CO/MeOH. It sublimes at 60o/high vacuum. Also dissolve it in pet ether, filter it through silica gel, evaporate and recrystallise it. [Steiger & Reichstein Helv Chim Acta 20 817 1937, Prelog et al. Helv Chim Acta 27 66 1944, IR, NMR: Halkes & Havinga Rec Trav Chim Pays-Bas 8 4 889 1965, Allinger et al. Tetrahedron 27 5073 1971, Beilstein 5 III 1110, 5 IV 1211.]
Properties of 5-ALPHA-ANDROSTANE
| Melting point: | 50-50.5° |
| Boiling point: | 336.0±9.0 °C(Predicted) |
| alpha | D16 +2° (c = 1.2 in chloroform) |
| Density | 0.950±0.06 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| CAS DataBase Reference | 438-22-2(CAS DataBase Reference) |
| EPA Substance Registry System | Androstane, (5.alpha.)- (438-22-2) |
Safety information for 5-ALPHA-ANDROSTANE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H373:Specific target organ toxicity, repeated exposure |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P281:Use personal protective equipment as required. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-ALPHA-ANDROSTANE
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