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HomeProduct name list5-ALPHA-ANDROSTANE

5-ALPHA-ANDROSTANE

Synonym(s):Etioallocholane

  • CAS NO.:438-22-2
  • Empirical Formula: C19H32
  • Molecular Weight: 260.46
  • MDL number: MFCD00067600
  • EINECS: 207-116-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-15 10:43:57
5-ALPHA-ANDROSTANE Structural

What is 5-ALPHA-ANDROSTANE?

The Uses of 5-ALPHA-ANDROSTANE

5alpha-Androstane is an anabolic steroid.

Definition

ChEBI: 5alpha-androstane is the 5alpha-stereoisomer of androstane. It has a role as a human metabolite.

Purification Methods

Purify 5-androstane by chromatography through Al2O3 (grade III) and elute with pet ether and recrystallise from MeOH (2x) and Me2CO/MeOH. It sublimes at 60o/high vacuum. Also dissolve it in pet ether, filter it through silica gel, evaporate and recrystallise it. [Steiger & Reichstein Helv Chim Acta 20 817 1937, Prelog et al. Helv Chim Acta 27 66 1944, IR, NMR: Halkes & Havinga Rec Trav Chim Pays-Bas 8 4 889 1965, Allinger et al. Tetrahedron 27 5073 1971, Beilstein 5 III 1110, 5 IV 1211.]

Properties of 5-ALPHA-ANDROSTANE

Melting point: 50-50.5°
Boiling point: 336.0±9.0 °C(Predicted)
alpha  D16 +2° (c = 1.2 in chloroform)
Density  0.950±0.06 g/cm3(Predicted)
storage temp.  room temp
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Solid
color  White to Off-White
CAS DataBase Reference 438-22-2(CAS DataBase Reference)
EPA Substance Registry System Androstane, (5.alpha.)- (438-22-2)

Safety information for 5-ALPHA-ANDROSTANE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
H336:Specific target organ toxicity,single exposure; Narcotic effects
H351:Carcinogenicity
H373:Specific target organ toxicity, repeated exposure
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P281:Use personal protective equipment as required.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 5-ALPHA-ANDROSTANE

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