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HomeProduct name list(4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE

(4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE

(4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE Structural

What is (4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE?

Chemical properties

White crystalline powder

Reactions

  1. Chiral ligand used in the asymmetric reduction of highly substituted olefins.
  2. Chiral ligand used in the enantioselective Heck reaction. The success of the reaction is due to the fact that the catalytic system does not promote double bond isomerization.
  3. Chiral ligand used in the entantioselective palladium-catalyzed allylic substitution of sodium benzotriazole.
  4. Decarboxylative allylic alkylation.
Reactions of 148461-14-7

Properties of (4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE

Melting point: 85-90 °C
Boiling point: 492.7±28.0 °C(Predicted)
alpha  -44° (c 1.4, CHCl3)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
form  Powder
pka 4.31±0.70(Predicted)
color  white
optical activity [α]20/D 48±3°, c = 1% in chloroform
Sensitive  air sensitive
BRN  5879302

Safety information for (4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE

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