4,6-Dichloro-5-nitropyrimidine

CAS NO.：4316-93-2
Empirical Formula: C4HCl2N3O2
Molecular Weight: 193.98
MDL number: MFCD00006107
EINECS: 224-340-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 4,6-Dichloro-5-nitropyrimidine?

Chemical properties

Yellow Crystalline Solid

The Uses of 4,6-Dichloro-5-nitropyrimidine

4,6-Dichloro-5-nitropyrimidine (cas# 4316-93-2) is a compound useful in organic synthesis.

Purification Methods

If too impure, then dissolve it in Et2O, wash it with H2O, dry it over MgSO4, evaporate it to dryness and recrystallise it from pet ether (b 85-105o) to give a light tan solid. It is soluble in ca 8 parts of MeOH [Boon et al. J Chem Soc 96 1951, Montgomery et al. in Synthetic Procedures in Nucleic Acid Chemistry Zorbach & Tipson eds, Wiley & Sons, NY, p76 1968]. [Beilstein 23 III/IV 899.]

Properties of 4,6-Dichloro-5-nitropyrimidine

Melting point:	100-103 °C (lit.)
Boiling point:	325.8±37.0 °C(Predicted)
Density	1.737±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	Chloroform, Ethyl Acetate, Methanol, Toluene
form	Solid
pka	-7.48±0.26(Predicted)
color	White to Off-White
BRN	162029
CAS DataBase Reference	4316-93-2(CAS DataBase Reference)
NIST Chemistry Reference	Pyrimidine, 4,6-dichloro-5-nitro-(4316-93-2)
EPA Substance Registry System	Pyrimidine, 4,6-dichloro-5-nitro- (4316-93-2)

Safety information for 4,6-Dichloro-5-nitropyrimidine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.