4,5-DIBROMO-O-XYLENE

Synonym(s):4,5-Dibromo-o-xylene

CAS NO.：24932-48-7
Empirical Formula: C8H8Br2
Molecular Weight: 263.96
MDL number: MFCD00082743
SAFETY DATA SHEET (SDS)
Update Date: 2023-12-26 17:07:23

What is 4,5-DIBROMO-O-XYLENE?

Chemical properties

White solid

The Uses of 4,5-DIBROMO-O-XYLENE

1,2-Dibromo-4,5-dimethylbenzene is used as a reagent in the synthesis of Thalidomide (T338850); an inhibitor of FGF-induced angiogenesis and replication of human immunodeficiency virus type 1. Also a teratogenic sedative and immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.

The Uses of 4,5-DIBROMO-O-XYLENE

1,2-Dibromo-4,5-dimethylbenzene can be used in the synthesis of alkylamino zinc(II)phthalocyanines, with potential application as photosensitizers in photodynamic therapy. It can also be used in the synthesis of 1,2-dibromo-4,5-bis(dibromomethyl)benzene via reaction with azobisisobutyronitrile.

General Description

1,2-Dibromo-4,5-dimethylbenzene can be synthesized via bromination of o-xylene.

Properties of 4,5-DIBROMO-O-XYLENE

Melting point:	85-89 °C (lit.)
Boiling point:	278 °C
Density	1.7485 (rough estimate)
refractive index	1.6146 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
color	White to Pale Yellow
BRN	2206183
CAS DataBase Reference	24932-48-7(CAS DataBase Reference)

Safety information for 4,5-DIBROMO-O-XYLENE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H413:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.