4-Phenyltoluene

Synonym(s):4-Methylbiphenyl

Prepared by catalytic reduction of p-phenyl benzyl alcohol obtained from p-phenyl benzoic acid.

White crystalline powder

p-Methyl diphenyl has a floral, spicy, wintergreen, anise, waxy, mint odor.

4-Phenyltoluene is used as a flavoring ingredient in the food industry. It also functions as a reagent used in organic and pharmaceutical synthesis.

By catalytic reduction of p-phenyl benzyl alcohol obtained from p-phenyl benzoic acid.

ChEBI: 4-Methylbiphenyl is a member of biphenyls.

Taste characteristics at 12 ppm: spicy, estragole, fennel, floral and wintergreen

Journal of the American Chemical Society, 92, p. 6088, 1970 DOI: 10.1021/ja00723a061
Tetrahedron Letters, 37, p. 3857, 1996 DOI: 10.1016/0040-4039(96)00699-5
The Journal of Organic Chemistry, 50, p. 3104, 1985 DOI: 10.1021/jo00217a018

Taste at 12 ppm

Melting point:	44-47 °C (lit.)
Boiling point:	267-268 °C (lit.)
Density	1,015 g/cm³
refractive index	1.5761 (estimate)
FEMA	3186 \| 4-METHYLBIPHENYL
Flash point:	>230 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Soluble in DMSO
form	powder to crystal
color	White to Orange to Green
Odor	at 1.00 % in dipropylene glycol. floral spicy wintergreen anise waxy mint
Water Solubility	Insoluble in water. Soluble in alcohol and ether, very soluble in organic solvents.
JECFA Number	1334
BRN	1904468
CAS DataBase Reference	644-08-6(CAS DataBase Reference)
NIST Chemistry Reference	1,1'-Biphenyl, 4-methyl-(644-08-6)
EPA Substance Registry System	1,1'-Biphenyl, 4-methyl- (644-08-6)

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.