4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
- CAS NO.:21561-09-1
- Empirical Formula: C16H15N3O2
- Molecular Weight: 281.31
- MDL number: MFCD01815294
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:06
What is 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE?
Description
WHI-P258 is a quinazoline compound that modeling studies suggested would bind to the active site of JAK3 with an estimated Ki value of 72 μM. However, it is inactive at JAK3 (IC50 = >300 μM) and has been used as a negative control for structurally similar compounds that inhibit platelet aggregation and herpes simplex virus 1 (HSV-1) replication.
The Uses of 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
4-Phenylamino-6,7-dimethoxyquinazoline is a specific inhibitors of Janus kinase 3 (JAK3).
Properties of 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
Boiling point: | 441.2±40.0 °C(Predicted) |
Density | 1?+-.0.06 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml |
form | A crystalline solid |
pka | 6.19±0.70(Predicted) |
color | White to off-white |
Safety information for 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
Computed Descriptors for 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-
JAK3 Inhibitor
WHI-P97
7-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE
WH-4-023
4-AMINO-3-CYANO-1,2,5,6-TETRAHYDROPYRIDINE
JAK3 INHIBITOR I
WEHI-345
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