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HomeProduct name list4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Structural

What is 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE?

Description

WHI-P258 is a quinazoline compound that modeling studies suggested would bind to the active site of JAK3 with an estimated Ki value of 72 μM. However, it is inactive at JAK3 (IC50 = >300 μM) and has been used as a negative control for structurally similar compounds that inhibit platelet aggregation and herpes simplex virus 1 (HSV-1) replication.

The Uses of 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

4-Phenylamino-6,7-dimethoxyquinazoline is a specific inhibitors of Janus kinase 3 (JAK3).

Properties of 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

Boiling point: 441.2±40.0 °C(Predicted)
Density  1?+-.0.06 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml
form  A crystalline solid
pka 6.19±0.70(Predicted)
color  White to off-white

Safety information for 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

Computed Descriptors for 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

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