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HomeProduct name list4-Nitropyridine N-oxide

4-Nitropyridine N-oxide

  • CAS NO.:1124-33-0
  • Empirical Formula: C5H4N2O3
  • Molecular Weight: 140.1
  • MDL number: MFCD00006206
  • EINECS: 214-395-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:15:30
4-Nitropyridine N-oxide Structural

What is 4-Nitropyridine N-oxide?

Chemical properties

white to light yellow crystal

The Uses of 4-Nitropyridine N-oxide

The N-oxide derivative of a nitrated pyridine that has been shown to inhibit Na,K-ATPase activity. 4-Nitropyridine N-Oxide is a quorum sensing inhibitor.

The Uses of 4-Nitropyridine N-oxide

4-Nitropyridine N-oxide may be used in the preparation of several 4-substituted pyridine-N-oxides and pyridines.

What are the applications of Application

4-Nitropyridine N-oxide is a quorum-sensing inhibitor

General Description

Solid.

Air & Water Reactions

May be deliquescent.

Reactivity Profile

Aromatic nitro compounds range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction.

Health Hazard

High toxicity via oral exposure.

Fire Hazard

When heated to decomposition, 4-Nitropyridine N-oxide emits very toxic fumes of nitrogen oxides. Avoid decomposing heat.

Safety Profile

Poison by ingestion and skincontact. Questionable carcinogen with experimentaltumorigenic data. Mutation data reported. Mixtures withdiethyl-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylateexplode when heated above 130°C. When heated todecompositio

Properties of 4-Nitropyridine N-oxide

Melting point: 159-162 °C (lit.)
Boiling point: 256.56°C (rough estimate)
Density  1.5657 (rough estimate)
refractive index  1.4800 (estimate)
storage temp.  Inert atmosphere,Room Temperature
solubility  soluble in DMSO
pka -1.37±0.10(Predicted)
form  Crystals or Powder
color  Yellow to brown
Water Solubility  insoluble
BRN  124331
CAS DataBase Reference 1124-33-0(CAS DataBase Reference)
NIST Chemistry Reference Pyridine-1-oxide, 4-nitro-(1124-33-0)
EPA Substance Registry System 4-Nitropyridine-1-oxide (1124-33-0)

Safety information for 4-Nitropyridine N-oxide

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
GHS Hazard Statements H300:Acute toxicity,oral
H301:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
H341:Germ cell mutagenicity
Precautionary Statement Codes P201:Obtain special instructions before use.
P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for 4-Nitropyridine N-oxide

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