4-Nitropyridine N-oxide

CAS NO.：1124-33-0
Empirical Formula: C5H4N2O3
Molecular Weight: 140.1
MDL number: MFCD00006206
EINECS: 214-395-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-05-13 18:00:15

What is 4-Nitropyridine N-oxide?

Chemical properties

white to light yellow crystal

The Uses of 4-Nitropyridine N-oxide

The N-oxide derivative of a nitrated pyridine that has been shown to inhibit Na,K-ATPase activity. 4-Nitropyridine N-Oxide is a quorum sensing inhibitor.

The Uses of 4-Nitropyridine N-oxide

4-Nitropyridine N-oxide may be used in the preparation of several 4-substituted pyridine-N-oxides and pyridines.

What are the applications of Application

4-Nitropyridine N-oxide is a quorum-sensing inhibitor

General Description

Solid.

Air & Water Reactions

May be deliquescent.

Reactivity Profile

Aromatic nitro compounds range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction.

Health Hazard

High toxicity via oral exposure.

Fire Hazard

When heated to decomposition, 4-Nitropyridine N-oxide emits very toxic fumes of nitrogen oxides. Avoid decomposing heat.

Safety Profile

Poison by ingestion and skincontact. Questionable carcinogen with experimentaltumorigenic data. Mutation data reported. Mixtures withdiethyl-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylateexplode when heated above 130°C. When heated todecompositio

Properties of 4-Nitropyridine N-oxide

Melting point:	159-162 °C (lit.)
Boiling point:	256.56°C (rough estimate)
Density	1.5657 (rough estimate)
refractive index	1.4800 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	soluble in DMSO
pka	-1.37±0.10(Predicted)
form	Crystals or Powder
color	Yellow to brown
Water Solubility	insoluble
BRN	124331
CAS DataBase Reference	1124-33-0(CAS DataBase Reference)
NIST Chemistry Reference	Pyridine-1-oxide, 4-nitro-(1124-33-0)
EPA Substance Registry System	4-Nitropyridine-1-oxide (1124-33-0)

Safety information for 4-Nitropyridine N-oxide

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H300:Acute toxicity,oral H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H341:Germ cell mutagenicity
Precautionary Statement Codes	P201:Obtain special instructions before use. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.