4-Methylcatechol

Synonym(s):3,4-Dihydroxytoluene;4-Methyl-1,2-benzenediol

CAS NO.：452-86-8
Empirical Formula: C7H8O2
Molecular Weight: 124.14
MDL number: MFCD00002205
EINECS: 207-214-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 20:33:22

What is 4-Methylcatechol?

Chemical properties

white to brown powder or chunks

The Uses of 4-Methylcatechol

4-Methylcatechol is used to synthesize antimicrobial, antioxidant. It also acts as effective inhibitor. It can be used to produce 4-bromo-5-methyl-pyrocatechol. It Increases Brain-Derived Neurotrophic Factor Content and mRNA Expression in Cultured Brain Cells and in Rat Brain In Vivo.

Definition

ChEBI: A methylcatechol having a single methyl substituent at the 4-position. It has been isolated from Picea abies.

Purification Methods

Crystallise the catechol from *C6H6. The purity is checked by TLC. Crystallise it from high-boiling pet ether and distil it in a vacuum. [Beilstein 6 IV 5878.]

Properties of 4-Methylcatechol

Melting point:	67-69 °C (lit.)
Boiling point:	251 °C (lit.)
Density	1.129 g/mL at 25 °C (lit.)
refractive index	1.5425 (estimate)
Flash point:	140 °C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Powder or Chunks
pka	9.91±0.10(Predicted)
Specific Gravity	1.129
color	White to brown
Water Solubility	soluble
BRN	636512
CAS DataBase Reference	452-86-8(CAS DataBase Reference)
NIST Chemistry Reference	1,2-Benzenediol, 4-methyl-(452-86-8)
EPA Substance Registry System	1,2-Benzenediol, 4-methyl- (452-86-8)

Safety information for 4-Methylcatechol

Signal word	Warning
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H301:Acute toxicity,oral H311:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.