4'-Isopropylacetophenone

Synonym(s):4′-Isopropylacetophenone

CAS NO.：645-13-6
Empirical Formula: C11H14O
Molecular Weight: 162.23
MDL number: MFCD00048297
EINECS: 211-433-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-05-27 17:30:58

What is 4'-Isopropylacetophenone?

Description

p-Isopropylacetophenone has an odor reminiscent of orris and basil. It has a warm, spicy flavor. May be synthesized by condensing cymene with acetyl chloride in the presence of AlCl3; also from benzol, acetyl chloride, and isopropyl chloride via Friedel Crafts.

Chemical properties

clear almost colorless to yellow liquid

Chemical properties

p-Isopropylacetophenone has a spicy, woody, herbaceous odor reminiscent of orris and basil. It has a warm, spicy flavor

Occurrence

Reported found in oil of lavandin, starfruit and dried bonito

The Uses of 4'-Isopropylacetophenone

4'-Isopropylacetophenone is used as perfuming agents. It is also used as flavoring and fragrance agent. Indenes are yielded from the derivatives if this compound in one step synthesis using a heterogeneous catalyst.

Preparation

By condensing cymene with acetyl chloride in the presence of AlCl3; also from benzol, acetyl chloride and isopropyl chloride via Friedel–Craft

Properties of 4'-Isopropylacetophenone

Melting point:	254 C
Boiling point:	119-120 °C (10 mmHg)
Density	0,97 g/cm³
refractive index	1.522-1.524
FEMA	2927 \| P-ISOPROPYLACETOPHENONE
Flash point:	238°C
storage temp.	Store below +30°C.
solubility	Chloroform (Slightly), Methanol (Sparingly)
form	Oil
color	Colourless
Odor	at 100.00 %. spicy woody herbal orris
Water Solubility	Soluble in alcohol. Insoluble in water.
JECFA Number	808
BRN	2205694
CAS DataBase Reference	645-13-6(CAS DataBase Reference)
NIST Chemistry Reference	Ethanone, 1-[4-(1-methylethyl)phenyl]-(645-13-6)
EPA Substance Registry System	4-Isopropylacetophenone (645-13-6)

Safety information for 4'-Isopropylacetophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.