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HomeProduct name list4-HYDROXYESTRONE

4-HYDROXYESTRONE

Synonym(s):1,3,5(10)-Estratriene-3,4-diol-17-one

4-HYDROXYESTRONE Structural

What is 4-HYDROXYESTRONE?

Chemical properties

Pale Yellow Solid

The Uses of 4-HYDROXYESTRONE

A metabolite of Estradiol

The Uses of 4-HYDROXYESTRONE

A metabolite of Estradiol.

What are the applications of Application

4-Hydroxy Estrone is An Estradiol metabolite

Definition

ChEBI: A 4-hydroxy steroid that is estrone substituted by a hydroxy group at position 4.

Hazard

A reproductive hazard.

Biochem/physiol Actions

4-Hydroxyestrone is an endogenous estrogen metabolite, which exhibits a strong neuroprotective effect against oxidative damage. It also provides effective protection against kanic acid-induced hippocampal oxidative damage in rats when compared to 17β-estradiol. 4-Hydroxyestrone regulates the angiogenic process during corpus luteum formation. It might be involved in an increased risk of cancer. 4-Hydroxyestrone is found in the early and mid-luteal phases.

Properties of 4-HYDROXYESTRONE

Melting point: 260-263°C
Boiling point: 468.2±45.0 °C(Predicted)
Density  1.241±0.06 g/cm3(Predicted)
Flash point: 93 °C
storage temp.  −20°C
solubility  DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form  Solid
pka 10.06±0.40(Predicted)
color  Pale Yellow to Light Brown

Safety information for 4-HYDROXYESTRONE

Computed Descriptors for 4-HYDROXYESTRONE

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