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HomeProduct name list4-HYDROXYCINNAMIC ACID (L-PHENYLALANINE METHYL ESTER) AMIDE

4-HYDROXYCINNAMIC ACID (L-PHENYLALANINE METHYL ESTER) AMIDE

4-HYDROXYCINNAMIC ACID (L-PHENYLALANINE METHYL ESTER) AMIDE Structural

What is 4-HYDROXYCINNAMIC ACID (L-PHENYLALANINE METHYL ESTER) AMIDE?

Description

Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 μM.

What are the applications of Application

N-[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-L-phenylalanine, methyl ester is an inhibitor of ACAT-1 and -2

Properties of 4-HYDROXYCINNAMIC ACID (L-PHENYLALANINE METHYL ESTER) AMIDE

storage temp.  Store at -20°C
solubility  DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:5): .5 mg/ml; Ethanol: 20 mg/ml
form  A crystalline solid

Safety information for 4-HYDROXYCINNAMIC ACID (L-PHENYLALANINE METHYL ESTER) AMIDE

Computed Descriptors for 4-HYDROXYCINNAMIC ACID (L-PHENYLALANINE METHYL ESTER) AMIDE

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