4-HYDROXY MEPHENYTOIN
Synonym(s):(±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylhydantoin;(±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylimididazolidine-2,4-dione
- CAS NO.:61837-65-8
- Empirical Formula: C12H14N2O3
- Molecular Weight: 234.25
- MDL number: MFCD00142316
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
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What is 4-HYDROXY MEPHENYTOIN?
Chemical properties
White Solid
The Uses of 4-HYDROXY MEPHENYTOIN
CYP2C19 metabolite of Mephenytoin
The Uses of 4-HYDROXY MEPHENYTOIN
Pharmacological activity investigating:• ;The drug effects on metabolization1• ;In vitro cytochrome P450 activity in microsomes2Analyte for electron-capture gas chromatography procedures3
The Uses of 4-HYDROXY MEPHENYTOIN
Pharmacological activity investigating:
- The drug effects on metabolization
- In vitro cytochrome P450 activity in microsomes
Analyte for electron-capture gas chromatography procedures
What are the applications of Application
(±)-4-Hydroxy Mephenytoin is a metabolite of mephenytoin
Definition
ChEBI: Hydroxymephenytoin is an imidazolidine-2,4-dione.
General Description
CYP2C19 metabolite of mephenytoin.
Biochem/physiol Actions
4-Hydroxymephenytoin catabolism displays genetic polymorphism and is a direct indicator of Cytochrome P450 2C19 (CYP2C19) activity. Detection and quantification of 4-hydroxymephenytoin in biological samples by HPLC method is well optimized.
Properties of 4-HYDROXY MEPHENYTOIN
Melting point: | 153-154 °C |
Density | 1.249±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO: >5mg/mL |
form | Solid |
pka | 8.31±0.70(Predicted) |
color | white |
Safety information for 4-HYDROXY MEPHENYTOIN
Computed Descriptors for 4-HYDROXY MEPHENYTOIN
New Products
1-Amino-1-cyclohexanecarboxylic acid 6-Bromo-3-iodo-1-methyl-1H-indazole 3-(2,4-Dimethoxybenzyl)dihydropyrimidine-2,4(1H,3H)-dione S-Methylisothiosemicarbazide hydroiodide ELECTROLYTIC IRON POWDER 1-Aminocyclobutanecarboxylic acid 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride tert-butyl 4-(1H-benzo[d]iMidazol-2-yl)piperidine-1-carboxylate Decanonitrile N,N'-diallyl-1,3-diaminopropanedihydrochloride N-(3-Nitrophenyl)cyclopropanecarboxamide (2-amino-2-phenylethyl)(methyl)amine Methyl-2-acetamidobenzoate methyl 6-chloro-2-(chloromethyl)nicotinate 2-methoxy-4-methyl-5-nitro pyridine 2-iodo-5-bromo pyridine 2-amino-4-methyl-5-nitro pyridine 4-cyano benzaldehyde 2-hydroxy-5-bromo pyridine 5-Fluoro-2-Oxindole 3,5-Dichloro-2,6-Dimethyl-1h-Pyridin-4-One (9H-fluoren-9-yl)methyl carbonochloridate 2-methyl-5-nitroaniline (S)-1-(tert-butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acidRelated products of tetrahydrofuran
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