4-HYDROXY MEPHENYTOIN
Synonym(s):(±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylhydantoin;(±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylimididazolidine-2,4-dione
- CAS NO.：61837-65-8
- Empirical Formula: C12H14N2O3
- Molecular Weight: 234.25
- MDL number: MFCD00142316
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is 4-HYDROXY MEPHENYTOIN?
Chemical properties
White Solid
The Uses of 4-HYDROXY MEPHENYTOIN
Pharmacological activity investigating:• ;The drug effects on metabolization1• ;In vitro cytochrome P450 activity in microsomes2Analyte for electron-capture gas chromatography procedures3
The Uses of 4-HYDROXY MEPHENYTOIN
CYP2C19 metabolite of Mephenytoin
The Uses of 4-HYDROXY MEPHENYTOIN
Pharmacological activity investigating:
- The drug effects on metabolization
- In vitro cytochrome P450 activity in microsomes
Analyte for electron-capture gas chromatography procedures
Definition
ChEBI: Hydroxymephenytoin is an imidazolidine-2,4-dione.
What are the applications of Application
(±)-4-Hydroxy Mephenytoin is a metabolite of mephenytoin
General Description
CYP2C19 metabolite of mephenytoin.
Biochem/physiol Actions
4-Hydroxymephenytoin catabolism displays genetic polymorphism and is a direct indicator of Cytochrome P450 2C19 (CYP2C19) activity. Detection and quantification of 4-hydroxymephenytoin in biological samples by HPLC method is well optimized.
Properties of 4-HYDROXY MEPHENYTOIN
| Melting point: | 153-154 °C |
| Density | 1.249±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: >5mg/mL |
| form | Solid |
| pka | 8.31±0.70(Predicted) |
| color | white |
Safety information for 4-HYDROXY MEPHENYTOIN
Computed Descriptors for 4-HYDROXY MEPHENYTOIN
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